Abstract
Aspergillus fumigatus catalase has been identified as an important antigen in pulmonary aspergillosis (PA) associated with a fungus ball or a lung infiltrate, and a rapid immuno-electrophoretic assay for catalase antibodies (“bubblography”) has been developed (H. Schonheyder, P. Andersen, J.C. Munck Petersen, 1985, Eur. J. Clin. Microbiol., 4:299). The diagnostic sensitivity for PA, excluding allergic bronchopulmonary aspergillosis, was 88% and the diagnostic specificity was 94%. The catalase antibody assay is well suited to the diagnostic laboratory, and a 2-year experience with the assay is reviewed with special reference to the correlation between catalase-specific antibodies and precipitins.
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© 1988 Plenum Press, New York
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Schönheyder, H.C. (1988). An Assessment of the Assay for Serum Antibodies to Aspergillus Fumigatus Catalase in the Diagnostic Laboratory. In: Drouhet, E., Cole, G.T., de Repentigny, L., Latgé, JP., Dupont, B. (eds) Fungal Antigens. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0773-0_61
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DOI: https://doi.org/10.1007/978-1-4613-0773-0_61
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-8075-0
Online ISBN: 978-1-4613-0773-0
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