The Antigenic and Allergenic Properties of Botrytis Cinerea
During aerobiological studies of fungal prevalence in the Netherlands (F. Beaumont et al., 1984, Ann. Allergy, 53:487) it was found that next to the commonly occurring genera such as Cladosporium, Penicillium, Alternaria and Aspergillus, the conidia of Botrytis belonged to the most prevailing airborne moulds. It was also found that Botrytis showed a high sensitization rate (6.1%) in a group of patients with bronchial obstructive complaints (F. Beaumont et al., 1985, Allergy, 40:181). Reports of Botrytis as a causative agent of human allergies are limited, but severe, early, and late obstructive reactions after inhalation of Botrytis extracts have been reported (Morrow-Brown, meeting of the “Foundation for Allergy Research in Europe”).