Antigenicity of CandidaAlbicans Cell Wall After Enzymatic Digestion
Studies of the cell wall of Candida albicans may provide significant data on the virulence mechanism(s) of this medically important fungus. The arrangement of wall components has a marked effect on the activity of various lytic enzymes used for protoplast production. Since the cell wall plays such an important role in antigenicity, we used selective enzymatic digestion as a method for examining the immunoreactivity of different wall components. The purpose of this study was to follow the cell wall degradation by various enzymes and the changes in antigenicity during wall digestion.