The Clinical Enzymology of the Complement System

  • Michael Loos
  • Jochem Alsenz


The complement (C) system is one of the most important humoral systems mediating many activities that contribute to inflammation and host defense, e.g. various anaphylatoxin activities, Chemotaxis and opsonization for phagocytosis. The C system is similar to other humoral systems, such as coagulation, fibrinolysis and the kinin system, a multifactoral system whose activation represents sequentially occurring multi-step activation cascades of the “classical” as well as the “alternative” pathway.


Systemic Lupus Erythematosus Complement System Classical Pathway Hereditary Angioedema Complement Deficiency 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Michael Loos
    • 1
  • Jochem Alsenz
    • 1
  1. 1.Institute of Medical MicrobiologyJohannes Gutenberg UniversityMainzGermany

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