Abstract
Ribosomal RNA serves as the backbone in ribosomal assembly and also, at least to some degree, as an active component of the mature ribosome. The introduction of nucleotide changes (e. g., by site-directed mutations) clearly offers the most promising tool for elucidating the function of ribosomal RNA.
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References
Boros, I., Kiss, A., and Venetianer, P., 1979, Nucleic Acids Res., 9:1817–1830.
Gourse, R. L., Takebe, Y., Sharrock, R. A., and Nomura, M., 1985, Proc. Natl. Acad. Sci., U.S.A , 82:1069–1073.
van Knippenberg, P. H., van Kimmenade, J. M. A., and Heus, H. A., 1984, Nucleic Acids Res., 12:2595–2604.
van Knippenberg, P. H., Heus, H. A., and van Buul, C. P. J. J., 1985, in “Gene Manipulation and Expression”, R. E. Glass and J. Spížek, eds., Croom Helm, London, pp 478–496.
Remaüt, E., Stanssens, P., and Fiers, W., 1981, Gene, 15:81–93.
Rüther, U., Koenen, M., Otto, K., and Müller-Hill, B., 1981, Nucleic Acids Res., 9:4087–4098.
Sedláček, J., Holoda, E., Fabry, M., and Rychlik, I., 1984, this series 5, pp 327–332.
Stark, M. J.R., Gourse, R. L., and Dahlberg, A. E., 1982, J. Mol. Biol., 159:417-439.
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© 1988 Plenum Press, New York
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Sedlácĉek, J., Smrt, J., Lakota, J., Rychlík, I., Fábry, M., Melzochová, O. (1988). A Site-Mutated rrsD Gene Expression Construct: Impairment of Ribosomal Function. In: Zelinka, J., Balan, J. (eds) Metabolism and Enzymology of Nucleic Acids. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0749-5_16
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DOI: https://doi.org/10.1007/978-1-4613-0749-5_16
Publisher Name: Springer, Boston, MA
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