In Vivo Metabolism of Apolipoproteins C-II Aid C-IIII in Normal and Hypertriglyceridemic Subjects

  • C. L. Malmendier
  • J.-F. Lontie
  • D. Dubois
  • C. Delcroix
  • T. Magot
  • L. De Roy
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 243)

Abstract

Two papers on apo C-II and apo C-III metabolism have been published in 1981 and 1982 (1,2), only one comparing normal and hypeirlipoproteinemic subjects (1). The kinetic analysis of 1 2 5l labeled VLDL was followed in plasma for 48 h only and there were no urine data. The essential limitation of these early studies was their short duration due to the low specific activity of each individual C peptide obtained after whole VLDL-apoprotein labeling (apo B, C, E) necessitating tedious and error-prone separation procedures.

Keywords

Cholesterol Albumin Carbohydrate EDTA Agarose 

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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • C. L. Malmendier
    • 1
  • J.-F. Lontie
    • 1
  • D. Dubois
    • 1
  • C. Delcroix
    • 1
  • T. Magot
    • 2
  • L. De Roy
    • 3
  1. 1.Fondation de Recherche sur l’AthéroscléroseBrusselsBelgium
  2. 2.Laboratoire de Physiologie de la NutritionUniversité de Paris-SudOrsayFrance
  3. 3.Hôpital MilitaireBrusselsBelgium

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