Relationship Between Structure and Metabolism of HDL Apolipoproteins; Study with Synthetic Peptides

  • Gabriel Ponsin
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 243)


In blood, lipids are transported in complex structures referred to as lipoproteins. These are formed of a monomolecular surface of phospholipids surrounding a core of neutral lipids (cholesterol esters and triglycerides)1. The polar phospholipid surface contains unesterified cholesterol and apolipoproteins. Apolipoproteins play several roles which may be summarized as follows:
  • They participate to the structural stability and to the solubility of lipoprotein particles.

  • Certain apolipoproteins act as effectors of lipolytic enzymes2,3.

  • Apolipoproteins may be recognized by specific receptors4–7.


Cholesterol Acyl Transferase Acyl Chain Length Amphipathic Helix Polar Face Hydrophobic Content 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • Gabriel Ponsin
    • 1
  1. 1.INSERM U. 197Laboratoire de Métabolisme des LipidesLyonFrance

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