Mineral Balance Study of Rats Fed Maillard Reaction Products

  • J. M. O’Brien
  • P. A. Morrissey
  • A. Flynn


Recent evidence suggests that certain products of the Maillard browning reaction in food may disturb mineral metabolism in humansl and in laboratory animals2. Stegink and co-workersl reported increases in urinary zinc, copper and iron in human subjects receiving Maillard reaction products intravenously. In this laboratory, dietary Maillard products of glucose/glutamate elevated the urinary excretion of calcium, magnesium, copper, zinc and sodium in rats2. The present study was conducted to examine the effects of Maillard reaction products of glucose/glutamate on mineral balance in the rat. Glutamic acid was selected as a source of amino groups because of its abundance as a free amino acid in foods.


Free Amino Acid Mineral Metabolism Monosodium Glutamate Maillard Reaction Product Mineral Balance 
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  1. 1.
    L.D. Stegink, J.B. Freeman, L. Den Besten and L.J. Filer, Maillard reaction products in parenteral nutrition, Prog. Fd. Nutr. Sci., 5: 265 (1981).Google Scholar
  2. 2.
    J. O’Brien, P.A. Morrissey and A. Flynn, The effect of Maillard reaction products on mineral homeostasis in the rat, in: “Proceedings of Euro Food Tox II”, Institute of Toxicology, Swiss Federal Institute of Technology, Zurich (1986).Google Scholar
  3. 3.
    R.M. Freeman and P.R. Taylor, Influence of histidine administration on zinc metabolism in the rat, Am. J. Clin. Nutr., 30: 523 (1977).PubMedGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • J. M. O’Brien
    • 1
  • P. A. Morrissey
    • 2
  • A. Flynn
    • 2
  1. 1.Departments of Food ChemistryUniversity CollegeCorkIreland
  2. 2.Departments of NutritionUniversity CollegeCorkIreland

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