Advertisement

Zn Deficiency in the Rat: Relationship between Growth and Metal Content and Distribution

  • D. H. Petering
  • B. Fowler

Abstract

Zinc deficiency causes many physiological changes in mammalian organisms1. The inhibition of growth is both a rapid and conspicuous effect. However, the underlying relationships between site of metal loss and its biological effects are not well understood. It is appreciated that cells and tissues need not lose large amounts of Zn to display signs of Zn deficiency. The present study was undertaken to examine carefully the distribution of Zn and Cu in the rat after it is placed on a Zn-deficient diet.

Keywords

Zinc Deficiency Organ Weight Deficient Diet Metal Loss Health Science Research 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    C. J. McClain Jr., E. J. Kasarskis, Jr., and J. S. Allen, Functional consequences of zinc deficiency. Prog. Food Nutr. Sci., 9: 185 (1985).PubMedGoogle Scholar
  2. 2.
    D. H. Petering, J. Loftsgaarden, J. Schneider, and B. Fowler, Metabolism of cadmium, zinc and copper in the rat kidney: the role of metallothionein and other binding sites. Environ. Health Persp. 54: 73 (1984).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1988

Authors and Affiliations

  • D. H. Petering
    • 1
    • 2
  • B. Fowler
    • 1
    • 2
  1. 1.Department of ChemistryUniversity of Wisconsin-MilwaukeeMilwaukeeUSA
  2. 2.The National Institute of Environmental Health SciencesResearch Triangle ParkUSA

Personalised recommendations