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Role of Natural Killer Cells in Inflammation and Antibacterial Activity

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Book cover Functions of the Natural Immune System

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Abstract

The purpose of this chapter is to review the evidence that large granular lymphocytes (LGL) can participate in the inflammatory response, with particular reference to bacterial infections. In this discussion, LGL will refer only to those cells that are identifiably of the natural killer (NK) cell lineage with respect to their membrane phenotype, in contrast to those LGL that may be derived from the T cell lineage. In this way, we will be referring to a natural effector population which has historically been associated with a nonrestricted lytic function and acts independently of the T cell receptor.

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  1. Manitoba Institute of Cell Biology, University of Manitoba, Winnipeg, Manitoba, R3E 0V9, Canada

    Arnold H. Greenberg

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  1. Frederick Cancer Research Facility, National Cancer Institute, Frederick, Maryland, USA

    Robert H. Wiltrout

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© 1989 Plenum Press, New York

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Greenberg, A.H. (1989). Role of Natural Killer Cells in Inflammation and Antibacterial Activity. In: Reynolds, C.W., Wiltrout, R.H. (eds) Functions of the Natural Immune System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0715-0_8

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  • DOI: https://doi.org/10.1007/978-1-4613-0715-0_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-8046-0

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