Abstract
The conversion of 7-dehydrocholesterol into vitamin D3 and that of bilirubin into more water soluble products, upon exposure of the body to UV-B (290–320 nm) and to visible light respectively, are two examples of systemic photobiological effects by endogenous compounds. Vitamin D3 is essential for proper bone calcification and the photoconversion of bilirubin in the visible light therapy of neonatal jaundice results in a decrease of brain-damaging effects. That simultaneous exposure to (sun)light and a xenobiotic may also result in systemic effects is indicated by results from animal experiments.
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© 1988 Plenum Press, New York
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Beijersbergen van Henegouwen, G.M.J., Busker, R.W., de Vries, H., Schoonderwoerd, S.A. (1988). Systemic Reactions in Phototoxicity. In: Douglas, R.H., Moan, J., Dall’Acqua, F. (eds) Light in Biology and Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0709-9_35
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DOI: https://doi.org/10.1007/978-1-4613-0709-9_35
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