Abstract
Our work shows that nucleolar dominance may be induced by hypomethylation of the NOR-chromosome. Hypomethylation of one of the two chromatids of both NOR-bearing chromosomes in a diploid cell was brought about in Allium cepa L. meristems by allowing one replication period in the presence of 10-6M 5-azacytidine (5AZA), while the replication period of the subsequent cell cycle took place with no 5AZA at all. When chromosomal segregation occurred at a second mitosis, each chromosome was randomly split in two non-equivalent halves: one with native DNA, the other having incorporated 5AZA. Such incorporation will transform this chromatid in the hypomethylated state.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1990 Plenum Press, New York
About this chapter
Cite this chapter
De la Torre, C., González-Fernández, A. (1990). DNA Methylation and Experimentally Induced Nucleolar Dominance. In: Harris, J.R., Zbarsky, I.B. (eds) Nuclear Structure and Function. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0667-2_37
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0667-2_37
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-7918-1
Online ISBN: 978-1-4613-0667-2
eBook Packages: Springer Book Archive