Interaction of T-2 Toxin with Cell Membranes

  • John R. DeLoach
  • George G. Khachatourians


The trichothecene mycotoxins are well studied and known to cause toxico- logical problems in man and animals.25 The most potent of this family of toxins is T-2 toxin. T-2 toxin is cytotoxic, having a radiomimetic effect on rapidly dividing cells. Immune function impairment has been reported for T-2 toxin both at the level of humoral immunity and cell mediated immunity.2,17,27


Phosphatidyl Choline Phosphatidyl Choline12 Sheep Erythrocyte Amino Acid Uptake Phenethyl Alcohol 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • John R. DeLoach
    • 1
  • George G. Khachatourians
    • 2
  1. 1.Veterinary Toxicology and Entomology Research LaboratoryUS Department of Agriculture, Agricultural Research ServiceCollege StationUSA
  2. 2.Department of Applied Microbiology and Food ScienceUniversity of SaskatchewanSaskatoonCanada

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