Predicting Memory Outcome from Medical Variables After Cardiac Surgery with Cardiopulmonary Bypass

  • Gregory W. Harter
  • J. Michael Williams
  • Wilborn George
  • Murry Mutchnick
  • Ivan Torres


Because the incidence of complications in CNS functioning is reportedly higher in cardiac surgeries requiring CPB than in other types of thoracic surgery without CPB assistance [1], the identification of risk factors has been of major concern in efforts to improve cerebral protection. A review of Barash [2] identified several factors that have been predictive of CNS complications in one or more studies: prolonged hypotension during CPB, overall duration of CPB, age of patient, previous neurological conditions, type and severity of heart disease, and specific components of the CPB process such as pulsatile versus nonpulsatile flow, type of oxygenator, degree and duration of hypothermia, and the use of filters in the circuit.


Coronary Artery Bypass Graft Medical Variable Cardiac Surgery Patient Previous Cardiac Surgery Left Main Coronary Artery Disease 
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  1. 1.
    M. Budabin, Neurologic complications of cardiac surgery, in: “Care of the Cardiac Surgical Patient,” R. Litvak and R. Jurado, eds., Appleton-Century-Crofts, Norwalk, CT (1982).Google Scholar
  2. 2.
    P. G. Barash, Cardiopulmonary bypass and postoperative neurologic dysfunction, Amer Heart J., 99: 675 (1980).PubMedCrossRefGoogle Scholar
  3. 3.
    R. Kolka, M. Hilberman, Neurological dysfunction following cardiac operation with low-flow, low-pressure, cardiopulmonary bypass, J. Thorac Cardiovasc Surg., 79:432 (1980).Google Scholar
  4. 4.
    K. M. Taylor, Brain damage during open heart surgery. Thorax, 37: 873 (1982).PubMedCrossRefGoogle Scholar
  5. 5.
    A. J. Lewis, “Mechanisms of Neurological Disease,” Little, Brown & Co., Boston (1976).Google Scholar
  6. 6.
    M. Little, J. M. Williams, C.J. Long, Clinical memory tests and everyday memory. Arch Clin Neuropsy., 1: 323 (1986).Google Scholar
  7. 7.
    J. M. Williams, “The Vermont Memory Scale: Initial Studies of Reliability and Validity,” Unpublished doctoral dissertation. University of Vermont (1983).Google Scholar
  8. 8.
    J. M. Williams, M. Little, S. Scates, N. Blockman, Memory complaints and abilities among depressed older adults, J Consul & Clin Psy., 55: 595 (1987).CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Gregory W. Harter
    • 1
  • J. Michael Williams
    • 2
  • Wilborn George
    • 3
  • Murry Mutchnick
    • 4
  • Ivan Torres
    • 4
  1. 1.Arkansas Rehabilitation InstituteLittle RockUSA
  2. 2.Hahnemann UniversityUSA
  3. 3.Methodist HospitalMemphisUSA
  4. 4.Memphis State UniversityMemphisUSA

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