Hydration as the Key Event in Mucificatton of the Rat Cumulus
The cumulus oophorus oocyte complex (OCC) is a unique structure in the mammalian female fertility system. The physiological role of the cumulus is to form the appropriate environment for the oocyte to develop, mature and prepare it for fertilization by the sperm. In the preovulatory stage, the cumulus exists as a compact-intact coat surrounding the oocyte. After maturation, the cumulus oophorus is expanded and transformed into a suspension of dissociated cells in a huge soft droplet of mucus, resulting in sperm-penetratable OCC.1–3
KeywordsHyaluronic Acid High Pressure Liquid Chromatography Uronic Acid Cumulus Cell Alcian Blue Staining
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