Non-Culture Tests for the Diagnosis of Gonorrhea
Gram-stain examination and culture of clinical specimens are the standard diagnostic tests for gonorrhea. However, both techniques have limitations. Gram stain is relatively insensitive for the diagnosis of cervical and rectal infections, and correct Interpretation of the Gram stain requires an experienced reader.1 Culture results may be unsatisfactory, unless selective culture medium is quality controlled, stored, and Inoculated properly, and promptly Incubated in a CO2-enriched atmosphere. Also the culture method using the common selective medium fails to detect vancomycin-susceptible strains of Neisseria gonorrhoeae. Further problems arise when specimens must be sent to another facility for culturing.
KeywordsCellulose Recombination Iodide Expense Vancomycin
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