Monte Carlo Study of Confidence Region Accuracy for MEG Inverse Dipole Solutions
Localization and characterization of neuromagnetic sources is often attempted assuming the model of a dipole current source in a spherical homogeneous conductor volume and solving the inverse problem for a given measured external field (Tanday (1987)). Evaluation of experimental results and clinical procedures also requires accurate confidence regions. Statistical methods exist for defining these regions by analyzing the fit of the data to the best fit model prediction without independent estimates of the measurement noise. We have empirically evaluated three of these methods in a Monte Carlo study.
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