Physiological Roles of Gap Junctional Communication in Reproduction

  • Robert C. Burghardt
  • William H. Fletcher


The uterus exhibits a unique structural and physiological plasticity when responding to ovarian cues with orderly cycles of tissue differentiation, glandular secretion, and regional turnover of terminally differentiated cells. These cyclic changes are programmed to be developmentally synchronous with blastocyst development, such that arrival of a blastocyst in the uterus, followed by interaction of blastocyst trophectoderm with uterine epithelial cells, results in the progressive phases of implantation.


Granulosa Cell Decidual Cell Uterine Smooth Muscle Uterine Epithelial Cell Myometrial Cell 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Robert C. Burghardt
    • 1
  • William H. Fletcher
    • 2
  1. 1.Department of Veterinary Anatomy, College of Veterinary MedicineTexas A&M UniversityCollege StationUSA
  2. 2.Department of Anatomy, School of MedicineLoma Linda University and Jerry L. Pettis Memorial Veterans Medical CenterLoma LindaUSA

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