Carbohydrate Intolerance and Impaired Pancreatic Insulin Release in Chronic Renal Failure: Role of Excess Blood Levels of Parathyroid Hormone

  • Shaul G. Massry
  • George Z. Fadda
  • Mohammad Akmal


Patients with chronic renal failure display abnormalities in carbohydrate metabolism (1–5). They almost always have resistance to the peripheral action of insulin (5, 6), while insulin secretion could be normal (4,7), increased (8,9) or decreased (3). Glucose intolerance is, therefore, usually encountered in uremic patients in whom both impaired tissue sensitivity to insulin and impaired secretion of the hormone co-exist (5,10).


Insulin Secretion Parathyroid Hormone Pancreatic Islet Parathyroid Gland Insulin Release 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Shaul G. Massry
    • 1
  • George Z. Fadda
    • 1
  • Mohammad Akmal
    • 1
  1. 1.Division of Nephrology and Department of MedicineUniversity of Southern California School of MedicineLos AngelesUSA

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