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Charge and Field Effects in Biosystems—2 pp 137–146Cite as

Glutamate Receptor Desensitization

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Abstract

Receptors for neurotransmitters found in the surface membranes of excitable cells, such as neurones, muscle fibres and endocrine cells exhibit desensitization or tachyphylaxis when exposed to high concentrations of agonists. This phenomenon of agonist-induced refractoriness has been best studied for the nicotinic and muscarinic acetylcholine receptors of vertebrate animals, although it has not yet been fully evaluated for any transmitter receptor.

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Author information

Authors and Affiliations

  1. Zoology Department, The University, Nottingham, NG7 2RD, UK

    Peter N. R. Usherwood & Robert L. Ramsey

Authors
  1. Peter N. R. Usherwood
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  2. Robert L. Ramsey
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Editor information

Editors and Affiliations

  1. Virginia Commonwealth University, Richmond, Virginia, USA

    M. J. Allen , S. F. Cleary  & F. M. Hawkridge ,  & 

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© 1989 Plenum Press, New York

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Usherwood, P.N.R., Ramsey, R.L. (1989). Glutamate Receptor Desensitization. In: Allen, M.J., Cleary, S.F., Hawkridge, F.M. (eds) Charge and Field Effects in Biosystems—2. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0557-6_14

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  • DOI: https://doi.org/10.1007/978-1-4613-0557-6_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7865-8

  • Online ISBN: 978-1-4613-0557-6

  • eBook Packages: Springer Book Archive

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