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Dietary Fiber and Lipid Absorption

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Dietary Fiber

Abstract

The regulation of lipid absorption by dietary means is a reasonable approach in reducing plasma lipids, particularly cholesterol. Among various dietary factors that interfere with lipid absorption, certain dietary fibers have a substantial hypolipidemic effect through interaction with lipids in the intestine (Kay, 1982; Kritchevsky, 1985; Miettinen, 1987; Vahouny, 1982, 1985a; Vahouny and Cassidy, 1985, 1986). Although the lipid-lowering effect of dietary fibers is rather moderate compared to synthetic compounds such as cholestyramine or colestipol, they usually exert no or otherwise negligible side effects (Cassidy et al., 1986, Furda, 1983). In addition, dietary fiber is relatively easily accepted as a constituent of regular meals. It has been shown that in low-fat diets recommended for the reduction of serum cholesterol, the effect of nonfat components such as protein, carbohydrate, and fiber of the diet on cholesterol lowering may become more important than the type of fat consumed (American Heart Association, 1986; Grundy, 1986; Report of the National Cholesterol Education Program, 1988).

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References

  • American Heart Association, 1986, Dietary guidelines for healthy American adults: A statement for physicians and health professionals by the Nutrition Committee, American Heart Association, Circulation 74:1465A–1468A.

    Google Scholar 

  • Asp, N.-G., Johansson, C.-G., Hallmer, H., and Siljestrom, M., 1983, Rapid enzymatic assay of insoluble and soluble dietary fiber, J. Agr. Food Chem 31:467–482.

    Article  Google Scholar 

  • Beynen, A. C., De Bruijne, J. J., and Katan, M. B., 1985, Treatment of young rats with cholestyramine or a hypercholesterolemic diet does not influence the response of serum cholesterol to dietary cholesterol in later life, Atherosclerosis 58:149–157.

    Article  CAS  Google Scholar 

  • Block, G., and Lanza, E., 1987, Dietary fiber sources in the United States by demographic group, J. Natl. Cancer Inst 79:83–91.

    CAS  Google Scholar 

  • Borgstrom, D., Barrowman, J. A., and Lindstrom, M., 1985, Role of bile acids in intestinal lipid digestion and absorption, in: Sterols and Bile Acids (H. Danielsson and J. Sjovall, eds.), Elsevier Science, Amsterdam, pp. 405–425.

    Chapter  Google Scholar 

  • Brown, M. S., and Goldstein, J. L., 1986, A receptor-mediated pathway for cholesterol homeostasis, Science 232:34–47.

    Article  CAS  Google Scholar 

  • Carey, M. L., Small, D. M., and Bliss, C. H., 1983, Lipid digestion and absorption, Annu. Rev. Physiol 45:651–677.

    Article  CAS  Google Scholar 

  • Cassidy, M. M., Fitzpatrick, L. R., and Vahouny, G. V., 1986, The effect of fiber in the postweaning diet on nutritional and intestinal morphological indices in the rat, in: Dietary Fiber, Basic and Clinical Aspects (G. V. Vahouny and D. Kritchevsky, eds.), Plenum Press, New York, pp. 229–251.

    Google Scholar 

  • Chen, I. S., Hotta, S. S., Ikeda, I., Cassidy, M. M., Sheppard, A. J., and Vahouny, G. V., 1987, Digestion, absorption and effects on cholesterol absorption of menhaden oil, fish oil concentrate and corn oil by rats, J. Nutr 117:1676–1680.

    CAS  Google Scholar 

  • Friedman, H. I., and Nylund, B., 1980, Intestinal fat digestion, absorption, and transport. A review, Am. J. Clin. Nutr 33:1108–1139.

    CAS  Google Scholar 

  • Furda, I., 1983, Aminopolysaccharides—their potential as dietary fiber, in: Unconventional Sources of Dietary Fiber (I. Furda, ed.), American Chemical Society, Washington, DC, pp. 105–122.

    Chapter  Google Scholar 

  • Gallo, L. L., Clark, S. B., Myers, S., and Vahouny, G. V., 1984, Cholesterol absorption in rat intestine: Role of cholesterol esterase and acyl coenzyme A: cholesterol acyltransferase, J. Lipid Res 25: 604–612.

    CAS  Google Scholar 

  • Gibson, J. C., 1984, Clinical and experimental method for the determination of cholesterol absorption, in: Laboratory and Research Methods in Biology and Medicine, Vol. 10 (J. A. Story, ed.), Alan R. Liss, New York, pp. 157–190.

    Google Scholar 

  • Grundy, S. M., 1983, Absorption and metabolism of dietary cholesterol, Annu. Rev. Nutr 3:71–96.

    Article  CAS  Google Scholar 

  • Grundy, S. M., 1986, Cholesterol and coronary heart disease: A new era, J.A.M.A 256:2849–2858.

    Article  CAS  Google Scholar 

  • Haln, P., and Kirby, L., 1973, Immediate and later effects of premature weaning and of feeding a high fat or high carbohydrate diet to weaning rats, J. Nutr 103:690–696.

    Google Scholar 

  • Ikeda, I., and Sugano, M., 1983, Some aspects of mechanism of inhibition of cholesterol absorption by β-sitosterol, Biochim. Biophys. Acta 732:651–658.

    Article  CAS  Google Scholar 

  • Imaizumi, K., and Sugano, M., 1986, Dietary fiber and intestinal lipoprotein secretion, in: Dietary Fiber, Basic and Clinical Aspects (G. V. Vahouny and D. Kritchevsky, eds.), Plenum Press, New York, pp. 287–308.

    Google Scholar 

  • Imaizumi, K., Tominaga, A., Mawatari, K., and Sugano, M., 1982, Effect of cellulose and guar gum on the secretion of mesenteric lymph chylomicrons in meal-fed rats, Nutr. Rep. Int 26:263–269.

    CAS  Google Scholar 

  • Kay, R. M., 1982, Dietary fiber, J. Lipid Res 23:221–242.

    CAS  Google Scholar 

  • Kritchevsky, D., 1985, Lipid metabolism and coronary heart disease, in: Dietary Fibre, Fibre-Depleted Foods and Disease (H. Trowell, D. Burkitt, and K. Heaton, eds.), Academic Press, London, pp. 305–315.

    Google Scholar 

  • Lu, Y.-F., Imaizumi, K., Sakono, M., and Sugano, M., 1989, Effects of dietary fibers in early weaning on later response of serum and fecal steroid levels to high-cholesterol diet in rats, Nutr. Res 9:345–352.

    Article  CAS  Google Scholar 

  • Miettinen, T. A., 1987, Dietary fiber and lipids, Am. J. Clin. Nutr 45:1237–1242.

    CAS  Google Scholar 

  • Nagata, Y., Ishiwaki, N., and Sugano, M., 1982, Studies on the mechanism of antihypercholesterolemic action of soy protein and soy protein-type amino acid mixture in relation to casein counterparts in rats, J. Nutr 112:1614–1625.

    CAS  Google Scholar 

  • Oku, H., and Sugano, M., 1986, Site of fat absorption and localization of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase activity along the small intestine of rats, Agr. Biol. Chem 50: 699–705.

    Article  CAS  Google Scholar 

  • Porzio, M. A., and Blake, J. R., 1983, Washed orange pulp: Charcterization and properties, in: Unconventional Sources of Dietary Fiber (I. Furda, ed.), American Chemical Society, Washington, DC, pp. 191–204.

    Chapter  Google Scholar 

  • Reiser, R., and Siedelman, Z., 1972, Control of serum cholesterol homeostasis by the cholesterol in the milk of the suckling rat, J. Nutr 102:1009–1016.

    CAS  Google Scholar 

  • Report of the National Cholesterol Education Program Expert Panel on Detection, 1988, Evaluation and treatment of high blood cholesterol in adults, Arch. Intern. Med 148:36–69.

    Article  Google Scholar 

  • Stange, E. F., and Dietschy, J. M., 1985, Cholesterol absorption and metabolism by the intestinal epithelium, in: Sterols and Bile Acids (H. Danielsson and J. Sjovall, eds.), Elsevier Science, Amsterdam, pp. 405–425.

    Google Scholar 

  • Story, J. A., 1986, Modification of steroid excretion in response to dietary fiber, in: Dietary Fiber, Basic and Clinical Aspects (G. V. Vahouny and D. Kritchevsky, eds.), Plenum Press, New York, pp. 253–264.

    Google Scholar 

  • Subbiah, M. T. R., 1983, Decreased atherogenic response to dietary cholesterol in pigeons after stimulation of cholesterol catabolism in early life, J. Clin. Invest 71:1509–1513.

    Article  CAS  Google Scholar 

  • Suckling, K. E., and Stange, E. F., 1985, Role of acyl-CoA:cholesterol acyltransferase in cellular cholesterol metabolism, J. Lipid Res 26:647–671.

    CAS  Google Scholar 

  • Sugano, M., Fujikawa, T., Hiratsuji, Y., Nakashima, K., Fukuda, N., and Hasegawa, Y., 1980, A novel use of chitosan as a hypocholesterolemic agent in rats, Am. J. Clin. Nutr 33:787–793.

    CAS  Google Scholar 

  • Sugano, M., Nakano-Morita, M., Yoshida, K., and Imai, J., 1988a, Influence of dietary apple and grape pomace on serum cholesterol level of the rat, J. Jpn. Soc. Food Sci. Technol 35:242–245.

    Article  CAS  Google Scholar 

  • Sugano, M., Watanabe, S., Kishi, A., Izume, M., and Ohtakara, A., 1988b, Hypocholesterolemic action of chitosans with different viscosity in rats, Lipids 23:187–191.

    Article  CAS  Google Scholar 

  • Sugano, M., Yamada, Y., Yoshida, K., Hashimoto, Y., Matsuo, T., and Kimoto, M., 1988c, The hypocholesterolemic action of the undigested fraction of soybean protein in rats, Atherosclerosis 72: 115–122.

    Article  CAS  Google Scholar 

  • Takebe, K., Makino, J., Konuma, T., Nakamura, T., Tsutsui, M., Osoino, K., Kudoh, M., Masuda, M., Tamasawa, N., and Ochiai, S., 1982, [Basic and clinical studies on apple fibre-Influence of the fibre on bile acid, blood glucose, plasma insulin, and plasma lipoprotein lipid] Newest Med 37: 2268–2274.

    Google Scholar 

  • Tasman-Jones, C. T., 1981, Effects of dietary fiber on the structure and function of the small intestine, Top. Gastroenterol 1981:67–74.

    Google Scholar 

  • Tasman-Jones, C. T., Owen, R. L., and Jones, A. L., 1982, Semipurified dietary fiber and small bowel morphology in rats, Dig. Dis. Sci 27:519–524.

    Article  CAS  Google Scholar 

  • Ting, S. V., and Rouseff, R. L., 1983, Dietary fiber from citrus waste: Characterization, in: Unconventional Sources of Dietary Fiber (I. Furda, ed.), American Chemical Society, Washington, DC, pp. 205–219.

    Chapter  Google Scholar 

  • Tso, P., 1985, Gastrointestinal digestion and absorption of lipid, Adv. Lipid Res 3:71–96.

    Google Scholar 

  • Vahouny, G. V., 1982, Dietary fiber, lipid metabolism and atherosclerosis, Fed. Proc 41:2801–2896.

    CAS  Google Scholar 

  • Vahouny, G. V., 1985a, Dietary fibers. Aspects of nutrition, pharmacology and pathology, in: Nutritional Pathology, Pathobiochemistry of Dietary Imbalance (H. Sidransky, ed.), Marcel Dekker, New York, pp. 207–320.

    Google Scholar 

  • Vahouny, G. V., 1985b, inhibition of cholesterol absorption by natural products, in: Drugs Affecting Lipid Metabolism, VIII (D. Kritchevsky, W. L. Holmes, and R. Paoletti, eds.), Plenum Press, New York, pp. 265–279.

    Google Scholar 

  • Vahouny, G. V., and Cassidy, M. M., 1985, Dietary fibers and absorption of nutrients, Proc. Soc. Exp. Biol. Med 180:432–446.

    CAS  Google Scholar 

  • Vahouny, G. V., and Cassidy, M. M., 1986, Dietary fiber and intestinal adaptation, in: Dietary Fiber, Basic and Clinical Aspects (G. V. Vahouny and D. Kritchevsky, eds.), Plenum Press, New York, pp. 181–209.

    Google Scholar 

  • Vahouny, G. V., Roy, T., Gallo, L. L., Story, J. A., Kritchevsky, D., and Cassidy, M. M., 1980, Dietary fibers III. Effects of chronic intake on cholesterol absorption and metabolism in the rat, Am. J. Clin. Nutr 33:2182–2191.

    CAS  Google Scholar 

  • Vahouny, G. V., Satchithanandam, S., Cassidy, M. M., Lightfoot, F. B., and Furda, I., 1983, Comparative effects of chitosan and cholestyramine on lymphatic absorption of lipids in the rat, Am. J. Clin. Nutr 38:699–705.

    Google Scholar 

  • Vahouny, G. V., Chalcarz, W., Satchithanandam, S., Adamson, I., Klurfeld, D. M., and Kritchevsky, D., 1984, effect of soy protein and casein intake on intestinal absorption and lymphatic transport of cholesterol and oleic acid, Am. J. Clin. Nutr 40:1156–1164.

    Google Scholar 

  • Vahouny, G. V., Khalafi, R., Satchithanandam, S., Watkins, D. W., Story J. A., Cassidy, M. M., and Kritchevsky, D., 1987, Dietary fiber supplementation and fecal bile acids, neutral steroids and divalent cations in rats, J. Nutr 117:2009–2015.

    CAS  Google Scholar 

  • Vahouny, G. V., Satchithanandam, S., Chen, I., Tepper, S. A., Kritchevsky, D., Lightfoot, F. G., and Cassidy, M. M., 1988, Dietary fiber and intestinal adaptation: Effects on lipid absorption and lymphatic transport in the rat, Am. J. Clin. Nutr 47:201–206.

    CAS  Google Scholar 

  • Watanabe, M., Oku, T., Shidoji, Y., and Hosoya, N., 1981, A new aspect on the mechanism of intestinal cholesterol absorption in rat, J. Nutr. Sci. Vitaminol 27:209–218.

    Article  CAS  Google Scholar 

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© 1990 Plenum Press, New York

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Sugano, M., Ikeda, I., Imaizumi, K., Lu, YF. (1990). Dietary Fiber and Lipid Absorption. In: Kritchevsky, D., Bonfield, C., Anderson, J.W. (eds) Dietary Fiber. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0519-4_9

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  • DOI: https://doi.org/10.1007/978-1-4613-0519-4_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4612-7846-7

  • Online ISBN: 978-1-4613-0519-4

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