Abstract
Aging has been reported to be the most common immune deficiency syndrome (Kay and Makinodan, 1981), since major pathological events and diseases are associated with advancing age. The decline in immune responsiveness affects both the T- and B-cell compartment, although T-cell functions seem to be the most impaired (Facchini et al., 1986, 1987). In particular, a reduced number of T-cell subsets (Abo et al., 1981) has been reported during human aging together with a depleted production of lymphokines as interleukin-2 (IL-2) and its receptor (IL-2R) (Gillis et al., 1981; Facchini et al., 1983).
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© 1990 Plenum Press, New York
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Degrassi, A. et al. (1990). Thymopentin Therapy in Elderly Patients with Chronic Bronchitis. In: Goldstein, A.L. (eds) Biomedical Advances in Aging. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0513-2_55
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DOI: https://doi.org/10.1007/978-1-4613-0513-2_55
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