Abstract
Aging is accompanied by a gradual decline of certain physiological functions. Not the least of these are the effector functions of the immune system. Most aging animals demonstrate a progressive decline in their capacity to mount primary immune responses when compared in magnitude and heterogeneity of antibody affinity with that seen in the immune response of young adult animals.
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© 1990 Plenum Press, New York
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Goidl, E.A., McEvoy, S.J.M., Bonilla, F.A., Kaushik, A., Bona, C.A. (1990). Regulation of the Expressed Idiotypic Repertoire in the Normal Immune Response of the Aged. In: Goldstein, A.L. (eds) Biomedical Advances in Aging. GWUMC Department of Biochemistry Annual Spring Symposia. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0513-2_40
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DOI: https://doi.org/10.1007/978-1-4613-0513-2_40
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