Is There a Need to Change the American Diet?

  • Johanna Dwyer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 401)

Abstract

Phytochemicals are substances found in edible fruits and vegetables, and other foods such as grains and legumes. They have the potential for decreasing chronic degenerative disease risks and thus are of interest. The other parts of this symposium have reviewed the fundamental science, mechanisms of action and effects of dietary fiber, the isothiocyanates, polyphenols, flavonoids, monoterpenes, and organosulfides. Now we turn to more practical questions about phytochemicals in the American diet. First, what should the scientific base be for evaluating the evidence? Second, what are the recommendations of expert groups today on these various phytochemicals? Third, are these recommendations being met? Fourth, is it time for Americans to consider changes in the amount or types of phytochemicals they eat to reduce risks for cancer or other chronic degenerative diseases? Finally, if it is time to implement such changes, how should this be done?

Keywords

Selenium Folic Acid Carotenoid Indole Polyphenol 

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References

  1. 1.
    Taylor MR. FDA’s public health goals in evaluating health claims. Crit Revs Food Science and Nutrition 35:1–5, 1995CrossRefGoogle Scholar
  2. 2.
    El Bayoumy K. Evaluation of chemopreventive agents against breast cancer proposed. Strategies for human clinical trials. Carcinogenesis 15 (11): 2395–420, 1994CrossRefGoogle Scholar
  3. 3.
    American Dietetic Association. Position of the American Dietetic Association: Phytochemicals and functional foods. J Am Diet Assoc 95:493 1995CrossRefGoogle Scholar
  4. 4.
    Interagency Board for Nutrition Monitoring and Related Research. Wright J, ed. Nutrition Monitoring in the United States: The Directory of Federal and State Nutrition Monitoring Activities. Hyattsville, MD: Public Health Service 1992, pg. 77Google Scholar
  5. 5.
    Woteki CE. Consumption, intake patterns, and exposure. Critical Revs in Food Science and Nutrition 35:143–147, 1995CrossRefGoogle Scholar
  6. 6.
    Dwyer JT. Future directions in food composition studies. J Nutrition Suppl 1994;124 (9S):1783S–1788S.Google Scholar
  7. 7.
    Ferguson LR, Yee RL, Scragg R, Metcalf PA, Harris PJ. Differences in intake of sppecfic food plants by Polynesians may explain their lower incidence of colorectal cancer compared with Europeans in New Zealand. Nutr Cancer 23: 33–42, 1995CrossRefGoogle Scholar
  8. 8.
    Cronin FJ, Krebs-Smith SM, Wyse BW, Light L. Characterizing food usage by demographic variables J AmDietet Assoc 81: 661, 1982Google Scholar
  9. 9.
    Patterson BH, Block G. Food choices and the cancer guidelines. Am J Public Health 78 (3):282, 1988CrossRefGoogle Scholar
  10. 10.
    Ryan AS, Martinez GA, Wysong JL, Davis MA. Dietary patterns of older adults in the United States, NHANES II, 1976–80. Am J Hum Biol 1:321, 1989CrossRefGoogle Scholar
  11. 11.
    Hendrich S, Lee K, Xu X, Wang HJ, Murphy PA. Defining food components as new nutrients. J Nutrition 124 (9 Suppl): 1789S–1792S, 1994Google Scholar
  12. 12.
    Hutchins AM, Lampe JW, Martini MC, Campbell DR, Slavin JL. Vegetables, fruits, and legumes: effect on urinary isoflavonoid phytoestrogen and lignan excretion. J Am Diet Assoc 95:769–774, 1995CrossRefGoogle Scholar
  13. 13.
    Irvine C, Fitzpatrick M, Robertson I, Woodhams D. The potential adverse effects of soybean phytoestrogens in infant feeding. NZ Med J 208–209, 24 May 1995Google Scholar
  14. 14.
    Cronin F J, Shaw A, Krebs Smith SM, Marsland P, Light L., Developing a food guidance system to implement the Dietary Guidelines. J Nutr Educ 19:281, 1987Google Scholar
  15. 15.
    Ip C, Lisk DJ. Enrichment of selenium in allium vegetables for cancer prevention. Carcinogenesis 15 (9):1881–5, 1994CrossRefGoogle Scholar
  16. 16.
    Haddad E. Development of a vegetarian food guide. Am. J. Clin. Nutr. 1994;59:1248S–54S.Google Scholar
  17. 17.
    Takada N, Kitaro M, Yono Y, Otari S, Fukoshama S. Enhancing effects of organosulfur compounds from garlic and onions on hepatocarcinogenesis in rats: association with cell proliferation and elevated ornithine decarboxylase activity. Jap J Cancer Res 85:1267–72, 1994Google Scholar
  18. 18.
    Chen MF, Chen LT, Boyce HW. Cruciferous vegetables and glutathione: their effects on colon mucosal glutathione level and colon tumor development in rats induced by DMH. Nutr Cancer 23:77–83, 1995CrossRefGoogle Scholar
  19. 19.
    Zhong Y, Talalay P. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Res 54 (7Supp): 1976S–1981S, 1994Google Scholar
  20. 20.
    Zhang Y, Kensler TW, Cho CG. Posner GH, Talalay P. Anticarcinogenic activities of sulforaphane and structurally-related synthetic norbornyl isothiocynates. Proc Natl. Acad. Sci. USA 91 (8):3147–50, 1994CrossRefGoogle Scholar
  21. 21.
    Zhang Y, Kolm RH, Mannewik B, Talalay P. Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases. Biochem Biophys Res Comm 206 (2):748–55, 1995CrossRefGoogle Scholar
  22. 22.
    Lee MS. Oxidative conversion of isothiocyanates to isocyanates by rat liver. Environ Health Perspectives 102 (S6):45–8, 1994Google Scholar
  23. 23.
    Meger, D.J., Crease, DJ. and Ketterer, B. Forward and reverse catalysis and product sequestration by human glutathione S transferases in the reaction of GSH with dietary aralkyl isothiocyanates. Biochem J 306 (2):565–9, 1995Google Scholar
  24. 24.
    Jiao D, Ho CT, Fooiles P, Chang FL. Identification and quantification of the N-acetylcysteine conjugate of allylisothiocynate in human urine after ingestion of mustard. Cancer Epi Biomarkers and Prevention 3 (6):487–92, 1994Google Scholar
  25. 25.
    Kore AM, Jeffrey DH, Wallig MA. Effects of 1-isothiocyanato-3- (methylsulfinyl) propane in xenobiotic metabolizing enzymes in rats. Food and Chemical Tox 31 (10):723–9, 1993CrossRefGoogle Scholar
  26. 26.
    Musk SR, Johnson IT. Allylisothiocyanate is selectively toxic to transformed cells of the human colorectal tumor HT 29 Carcinogenesis 14 (10):2079–83, 1993CrossRefGoogle Scholar
  27. 27.
    Graham HN. Green tea composition, consumption and polyphenol chemistry. Preventive Med 21:334–50, 1992CrossRefGoogle Scholar
  28. 28.
    Komori A, Yatsumoni J, Okake S, Abe S, Hara K, Suganoma M, Kim SJ, Fujiki H. Anticarcinogenic activity of green tea polyphenols. Jap J Clin Oncology 23 (3): 186–90, 1993Google Scholar
  29. 29.
    Wong ZY, Huang MT, Ho CT, Chang R, Ma W, Ferraro T, Reghl KR, Yang CS, Conney AH. Inhibiting effect of green tea on the growth of established skin papillomas in mice. Cancer Res 52 (23):6657–65, 1992Google Scholar
  30. 30.
    Fuhrman B, Lary A, Arion M. Consumption of red wine with meals reduces susceptibility of human plasma and LDL to lipid peroxidation. AJCN 61 (3):549–54, 1995Google Scholar
  31. 31.
    Ho CT, Chan Q, Shi H, Zhang KQ,and Rosen R.T., Antioxidativeeffect of polyphenol extract prepared from various Chinese teas, Prev. Med. 21:520 (1992)CrossRefGoogle Scholar
  32. 32.
    Attaway JA. Medical benefits of juice flavonoids, pp 207–217 in Report of Congress: XI International Congress of Fruit Juice, Sao Paulo, 1991Google Scholar
  33. 33.
    Kuhnau J.The flavonoids. A class of semi-essential food components: their role in human nutrition. World Review of Nutrition and Dietetics 1976;24:117–91Google Scholar
  34. 34.
    Pierpoint WS. Flavonoids in the human diet. In: Cody V, Middleton EJ, Harbone JB, eds. Flavonoids in Biology and Medicine: Biochemical, Pharmacological, and Structure-Activity Relationships. Vol. 213. Alan R.Liss,Inc, New York; 1986; 125–40Google Scholar
  35. 35.
    Herrmann K. Flavonols and flavones in food plants: a review. J Food Technol 1976; 11:433–48CrossRefGoogle Scholar
  36. 36.
    Crowell PL, Gould MN. Chemoprevention and therapy of cancer by d-limonene, Crit Reviews Oncogenesis 5 (1): 1–22, 1994Google Scholar
  37. 37.
    Elson CE, YU SG. Chemoprevention of cancer by merulonate derived constituents of fruits and vegetables. Nutr 124:607–14, 1994Google Scholar
  38. 38.
    Crowell PP, Elson CE, Bailey HH, Elegbade A, Haag JD, Gould MN. Human metabolism of the experimental cancer therapeutic agent d-limonene. Cancer Chemotherapy and Pharmacology 35 (1):31–7, 1994CrossRefGoogle Scholar
  39. 39.
    Redely BS, Rug CV, Revenson A, Kellogg G. Chemoprevention of colon carcinogenesis by organosulfide compounds. Cancer Res 53 (15):3493–8, 1993Google Scholar
  40. 40.
    Dorant E, van den Brundt PA, Goldbohm RA. Allium vegetable consumption, garlic supplement intake and female breast carcinoma incidence. Breast Cancer Research and Treatment 33 (2): 163–70, 1995CrossRefGoogle Scholar
  41. 41.
    Dorant E, van den Brandt PA, Goldbohm RA. A prospective cohort study on allium vegetable consumption, garlic supplement use and risk of lung carcinoma in the Netherlands. Cancer Res 54:6148–53, 1994Google Scholar
  42. 42.
    Brenner S, Wolf R. Possible nutritional factors in induced pemphigus. Dermatology 189 (4):337–9, 1994CrossRefGoogle Scholar
  43. 43.
    Barnes S, Peterson G, Grubbs C, Setchell K. Chapter 10:Potential role of dietary isoflavones in the prevention of cancer pg 135–146 in Jacobs MM, ed. Diet and Cancer: Markers, Prevention, and Treatment. Plenum Press New York, 1994Google Scholar
  44. 44.
    Thompson LU. Antioxidant and hormone mediated health benefits of whole grains. Critical Reviews in Food Science and Nutrition 34 (5 &6): 473–497, 1994CrossRefGoogle Scholar
  45. 45.
    Gridley G, McLaughlin JK, Block G, Blot WJ, Fraumeni JF Vitamin supplement use and reduced risk of oral and pharyngeal cancer. Am J Epidemiol 135:1083, 1992Google Scholar
  46. 46.
    Fotsis T, Pepper M, Adlercreutz H, Hase T, Montesano R, Schweigerer L. Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis. J Nutrition 125 (3 Suppl):790S–797S, 1995Google Scholar
  47. 47.
    Franke AA, Custer LJ,Cerna CM, Narala K. Rapid HPLC analysis of dietary phytoestrogens from legumes and from human urine. Proc Soc Exper Biol Med 208:18–26, 1995Google Scholar
  48. 48.
    Whitten PL, Lewis C, Russell E, Naftolin F. Potential adverse effects of phytoestrogens. J Nutrition 125 (3 Suppl):771S–776S, 199Google Scholar

Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Johanna Dwyer
    • 1
  1. 1.Frances Stern Nutrition Center, New England Medical Center and Schools of Medicine and NutritionTufts UniversityBostonUSA

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