Transport of Various Forms of L-Tryptophan in the Small Intestine of Chicks

Mechanism and Regulation
  • N. Basova
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 398)


Tryptophan belongs under the irreplacable amino acids, the presence of which is needed in the ration for keeping up the life of organism. The ways of their absorption in mammal intestines were studied by Munck and Rasmussen (1975). They had stated that the entrance of L-tryptophan across the apical membrane of enterocytes was performed by the carriers of neutral amino acids. At its exit across the basolateral membrane a mechanism is used common with L-lysine. The study of mechanism for L-tryptophan absorption has been carried out on chicks in our laboratory as well. At this investigation the active character of L-tryptophan transport process was found out, its stereospeciflcity was revealed as well as dependence of the presence of sodium and hydrogen ions in the incubation medium and the presence of oxygen in it. A stimulating impact of a number of L-amino acids and carbohydrates was observed on the absorption of this irreplacable amino acid (Kushak et al., 1984; Kushak and Basova, 1987; Basova and Kushak, 1987).


Small Intestine Neutral Amino Acid Rabbit Jejunum Mammal Intestine Sensitive Spectrophotometric Method 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • N. Basova
    • 1
  1. 1.Institute of BiologyLatvian Academy of SciencesLatviaUSA

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