Variations of Free and Total Tryptophan Serum Levels After GN-RH Administration in Patients with Amenhorrea

Preliminary Results
  • N. Carretti
  • C. V. L. Costa
  • A. Bertazzo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 398)


Tryptophan is present in the serum in two forms: free (FT) and linked to the proteins, total tryptophan (TT) comprises both fractions. The fraction FT which is detached continuously from the proteinic link is able to pass the hemato-encephalic barrier and is utilized as a precursor for the formation of cerebral serotonin (McMenamy et al., 1957; Knott and Curzon, 1972).


Menstrual Cycle Interpolation Curve Tryptophan Level Free Tryptophan Brain Tryptophan 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • N. Carretti
    • 1
  • C. V. L. Costa
    • 2
  • A. Bertazzo
    • 2
  1. 1.Istituto di Clinica Ostetrica e Ginecologica dell’Università di SienaSienaItaly
  2. 2.Dipartimento di Scienze Farmaceutiche dell’Università di PadovaPadovaItaly

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