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Tryptophan and Atherosclerosis

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Recent Advances in Tryptophan Research

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 398))

Abstract

The association between hypercholesterolemia and atherosclerosis in humans is widely accepted (Goldstein and Brown, 1977; Steinberg, 1983; Nordoy and Goodnight, 1990). Some studies (Muldoon et al., 1990) have shown that a decrease in serum cholesterol in middle-aged subjects by diet, drugs or both, leads to a significant reduction of the incidence of coronary heart disease, although total mortality is not affected by treatment, while higher mortality due to suicide or violence is observed among people undergoing treatment to lower serum cholesterol concentrations. Therefore, Engelberg (1992) suggested association between serum cholesterol levels, neuronal function and behavioural predisposition. The same author found that anomalies in brain serotonin were associated to reduced control of instinctive impulses.

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© 1996 Plenum Press, New York

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Baldo-Enzi, G., Baiocchi, M.R., Bertazzo, A., Costa, C.V.L., Allegri, G. (1996). Tryptophan and Atherosclerosis. In: Filippini, G.A., Costa, C.V.L., Bertazzo, A. (eds) Recent Advances in Tryptophan Research. Advances in Experimental Medicine and Biology, vol 398. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0381-7_67

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  • DOI: https://doi.org/10.1007/978-1-4613-0381-7_67

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8026-9

  • Online ISBN: 978-1-4613-0381-7

  • eBook Packages: Springer Book Archive

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