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Is an Altered Tryptophan Metabolism Responsible for Age-Related Cataract?

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Recent Advances in Tryptophan Research

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 398))

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Abstract

Senile cataract remains one of the major health concerns of the world with approximately 17 million people blind as a result of this disease (Ohrloff, 1989).

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References

  • Allegri G. and Angi M., 1981, Free and total tryptophan in senile cataract. Lancet2:157.

    Article  CAS  Google Scholar 

  • Costa C., Angi M., De Cari M., Vanzan S. and Allegri G., 1982, Metabolism and serum levels of tryptophan in senile cataract patients. Boll.Soc.It.BiolSperi. LVIII:333.

    Google Scholar 

  • Cotlier E. and Sharma Y., 1980, Plasma tryptophan in senile cataract. Lancet15:607.

    Article  Google Scholar 

  • Dilley K. and Pirie A., 1974, Changes to the proteins of the human lens nucleus in cataract. Exp.Eye Res.19:59.

    Article  CAS  Google Scholar 

  • Dillon J. and Spector A., 1976, Identification of beta-carbolines isolated from fluorescent human lens proteins. Nature259:422.

    Article  CAS  Google Scholar 

  • Elderfield A.J., Truscott R.J.W., Gan I., Schier G., 1989, A method for the separation of tryptophan metabolites by rp-HPLC with amperometric and fluorescence detection. J.Chromatog.495:71.

    Article  CAS  Google Scholar 

  • Harding J., and Crabbe M., 1984, The Lens:development, proteins, metabolism and cataract in: The Eye, H.Davson, ed. Academic Press, Inc. London.

    Google Scholar 

  • Ogino S. and Ichihara T., 1957, Biochemical studies on cataract:biochemical genesis of senile cataract. Am. J. Ophthalmol.43:754.

    CAS  Google Scholar 

  • Ohrloff C., 1989, Epidemiology of senile cataract. Dev. Ophthalmol.17:1.

    CAS  Google Scholar 

  • Truscott R.J.W. and Augustyn R.C., 1977, Changes in human lens nucleus in cataract. Exp.Eye Res.24:159.

    Article  CAS  Google Scholar 

  • Truscott R.J.W., Faull K. and Augustyn R.C., 1977, The identification of anthranilic acid in proteolytic digests of cataractous lens proteins. Ophthalmol.Res.9:263.

    Article  CAS  Google Scholar 

  • Truscott R.J.W., Pyne S. and Manthey M., 1991, Reactive metabolite hypothesis for human senile cataract. Lens Eye Tox.Res.8:251.

    CAS  Google Scholar 

  • Van Heyningen R., 1971, Fluorescent glucoside in the human lens. Nature230:393.

    Article  Google Scholar 

  • Wood A. and Truscott R.J.W., 1993, UV filters in the human lens:tryptophan catabolism. Exp. Eye Res.56:317.

    Article  CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Biochemistry Department, Illawarra Regional Hospital Wollongong, NSW, Australia

    A. J. Elderfield & R. J. W. Truscott

  2. The Australian Cataract Research Foundation, University of Wollongong, Northfields Avenue, Wollongong, NSW, Australia

    A. J. Elderfield & R. J. W. Truscott

Authors
  1. A. J. Elderfield
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  2. R. J. W. Truscott
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Editor information

Editors and Affiliations

  1. University Of Padova, Padova, Italy

    Graziella Allegri Filippini , Carlo V. L. Costa  & Antonella Bertazzo ,  & 

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© 1996 Plenum Press, New York

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Elderfield, A.J., Truscott, R.J.W. (1996). Is an Altered Tryptophan Metabolism Responsible for Age-Related Cataract?. In: Filippini, G.A., Costa, C.V.L., Bertazzo, A. (eds) Recent Advances in Tryptophan Research. Advances in Experimental Medicine and Biology, vol 398. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0381-7_66

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  • DOI: https://doi.org/10.1007/978-1-4613-0381-7_66

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8026-9

  • Online ISBN: 978-1-4613-0381-7

  • eBook Packages: Springer Book Archive

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