Abstract
Historically, toxins from plants are associated with murder, assassination and suicide (Mann, 1992). The deaths of several famous historical figures have directly or indirectly involved toxins from poisonous plants. Socrates’ forced suicide involved a toxic alkaloid from poison hemlock (Conium maculatum), while the many victims of Livia (wife of Emperor Augustus) and Agrippina (wife of Claudius) succumbed to the toxic tropane alkaloids of deadly nightshade (Atropa belladona). Cleopatra is reported to have tested the extracts of several poisonous plants including henbane (Hyoscyamus niger), deadly nightshade and nux-vomica (Strychnos nu-vomica) on her slaves before she chose the asp.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Addor, R. W. 1995. Insecticides. In: Agrochemical From Natural Products, Godfrey, C. R. A., ed. New York, Marcel Dekker, pp. 1–62.
Alkondon, M., Pereira, E. F. R., Wonnacott, S., and Albuquerque, E. X. 1992. Blockage of Nicotinic Currents in Hippocampal Neurons Defines Methyllycaconitine as a Potent and Specific Receptor Antagonist. Molecular Pharmacology 41:802–808.
Baker, D. C, and Keeler, R. F. 1991. Myopathy in Cattle Caused by Thermopsis montana. In: Toxicology of Plant and Fungal Compounds-Handbook of Natural Toxins, Vol.6, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker, pp. 61–82.
Baker, D. C, Keeler, R. F., and Gaffield, W. 1989. Pathology in Hamsters Administered Solanum Plant Species That Contain Steroidal Alkaloids. Toxicon 27:1331–1337.
Baker, D. C, Keeler, R. F., and Gaffield, W. 1988. Mechanism of Death in Hamsters Gavaged Potato Sprout Material. Toxicological Pathology 16:333 –339.
Baumeister, R. G. H., Schievelbein, H., and Zickgraf–Rudel, G. 1975. Toxicological and Clinical Aspects of Cyanide Metabolism. Drug Research 25:1056–1064.
Bell, E. A. 1985. The Biological Significance of Secondary Metabolites in Plants. In: Plant Toxicology, Seawright, A. A., Hegarty, M. P. J. L. F., and Keeler, R. F., eds. Yeerongpilly. Queensland. Queensland Dept. of Primary Industries, Animal Research Institute, pp. 50–56.
Benn, M. H., and Jacyno, J. 1983. The Toxicology and Pharmacology of Diterpenoid Alkaloids. In: Alkaloids: Chemical and Biological Perspectives, Vol.1, Pelletier, S. W., ed. New York, Wiley & Sons. pp. 153–210.
Binns, W., James, L. F., Shupe, J. L., and Thacker, E. J. 1962. Cyclopian– Type Malformations in Lambs. Archives of Environmental Health 5:106–108.
Bowers, W. S. 1982. Toxicology of the Precocenes. In: Insecticide Mode of Action, Coats, J. R., ed. New York, Academic Press, pp. 403–427.
Bowers, W. S., Ohta, T., Cleere, J. S., and Marsella, P. A. 1976. Discovery of Insect Anti–Juvenile Hormones in Plants. Science 193:542–547.
Brower, L. P., Seiber, J. N., Nelsen, C. J., Lynch, S. P., and Tuskes, P. M. 1982. Plant Determined Variation in the Cardenolide Content and Emetic Potency of Monarch Butterflies, Danaus plexippus, Reared on the Milkweed Asclepias eriocarpa in California. Journal of Chemical Ecology 8:579–633.
Brower, L. P. 1969. Ecological Chemistry. Scientific American 220:22–29.
Brower, L. P., Ryerson, W. N., Coppinger, L. L., and Glazier, S. C. 1968. Ecological Chemistry and the Payability Spectrum. Science 188:9–25.
Brown, D., and Keeler, R. F. 1978. Structure–Activity Relation of Steroid Teratogens:3. Solanidan-epimers. Journal of Agricultural and Food Chemistry 26:566–569.
Bull, L. B., Culvenor, C. C. J., and Dick, A. T. 1968. The Pyrrolizidine Alkaloids: Their Chemistry, Pathogenicity and Other Biological Properties. New York, North Holland Publishing Co., John Wiley and Sons. 293 pp.
Bull, L. B., Culvenor, C. C, Keast, J. C, and Edgar, G. 1956. An Experimental Investigation of the Hepatotoxic and of Other Effects on Sheep of the Consumption of Heliotropium europaeum L.: Heliotrope Poisoning of Sheep. Australian Journal of Agricultural Research 7:281–332.
Casida, J. E., and Quistad, G. B., eds. 1994. Pyrethrum Flowers: Production, Chemistry, Toxicology and Uses. New York, University Press. pp93–l 15.
Catterall, W. A. 1980. Neurotoxins That Act on Voltage–Sensitive Sodium Channels in Excitable Membranes. Annual Reviews in Pharmacology and Toxicology 20:15–43.
Cheeke, P. R., ed. 1989a. Toxicants of Plant Origin. Vol. 1. Alkaloids. Boca Raton, FL, CRC Press. 335 pp.
Cheeke, P. R., ed. 1989b. Toxicants of Plant Origin. Vol. 2 Glycosides. Boca Raton, FL, CRC Press. 277 pp.
Cheeke, P. R., ed. 1985. Natural Toxins in Feeds and Poisonous Plants. Boca Raton, FL, CRC Press. 287 pp.
Coats, J. R. 1994. Risks From Natural Versus Synthetic Insecticides. In: Annual Review of Entomology, Vol.39, Mittler, T. E., Radovsky, F. J., and Resh, V. H., eds. Palo Alto, Annual Reviews Inc. pp. 489–515.
Colegate, S. M., Dorling, P. R., and Huxtable, P. R. 1991. Swainsonine: a Toxic Indolizidine Alkaloid from the Australian Swainsona species. In: Toxicology of Plant and Fungal Compounds-Handbook of Natural Toxins, Vol.6, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker, pp. 159–189.
Corbett, J. R. 1984. Insects Acting Elsewhere in the Nervous System.. In: The Biochemical Mode of Action of Pesticides, Corbett, J. R., Wright, K., and Baillie, A.C. eds. London, Academic Press, pp. 141–178.
Dobelis, P., Madl, J. E., Manners, G. D., Pfister, J. A., and Walrond, J. P. 1993. Antagonism of Nicotinic Receptors by Delphinium Alkaloids. Neuroscience Abstracts 631:12.
Dorling, P. R., Colegate, S. R., and Huxtable, C. R. 1993. Plants Affecting Livestock: an Approach to Toxin Isolation. In: Bioactive Natural Products, Colegate, S. R., and Molyneux, R. J. eds. Boca Raton, FL, CRC Press, pp. 481–506.
Dorling, P. R., Huxtable, C. R., and Vogel, P. 1978. Lysosomal Storage in Swainsonia spp. Toxicosis. Neuropathology and Applied Neurobiology 4:285–295.
Dozortseva-Kubanova, P. M. 1959. Pharmacology of the Alkaloid Methyllycaconitine (Mellictine). Farmak-ologiya i Toksikologiya (Moscow) 22:30–33.
Duffey, S. S., and Scudder, G. G. E. 1974. Cardiac glycosides in Oncopeltus fasciatus (Dallas) Hemiptera:Ly-gaeidae. I. The Uptake and Distribution of Natural Cardenolides in the Body. Canadian Journal of Zoology 52:283–290.
Duffey, S. S., and Scudder, G. G. E. 1972. Cardiac Glycosides in North American Asclepiadacae, a Basis for Unpalatability in Brightly Coloured Hemiptera and Coleóptera. Journal of Insect Physiology 18:63–68.
Egekeze, J. O., and Oehme, F. W. 1980. Cyanides and Their Toxicity: a Literature Review. The Veterinary Quarterly:104–114.
Einhellig, F. A., and Leather, G. R. 1988. Potentials for Exploiting Allelopathy to Enhance Crop Production. Journal of Chemical Ecology 14:1831–1844.
Einhellig, F. A. 1987. Interactions Among Allelochemicals and Other Stress Factors of the Plant Environment. In: Allelochemicals: Role in Agriculture and Forestry, Waller, G. D., ed. ACS Symposium Series, 330. Washington, DC, American Chemical Society, pp. 343–357.
Elbert, A., Overbeck, H., Iwaya, K., and Tsuboi, S.. 1990. Inidacloprid, a Novel Systemic Nitromethylene Analogue Insecticide for Crop Protection. In: Brighton Crop Protection Conference-Pests and Diseases, Vol.1,. Surrey, UK, The British Crop Protection Council, pp. 21–39.
Ellinger, C. A., Haddon, W. F., Harden, L., Waiss Jr., A. C, and Wong, R. Y. 1994. Insect Inhibitory Steroidal Saccharide Esters from Physalis peruviana. Journal of Natural Products 57:348–356.
Elliott, M., Farnham, A. W., Janes, N. F., Johnson, D. M., and and Pulman, D. A. 1987. Synthesis and Insecticidal Activity of Lipophilic Amides. Parts 1–4: Pesticide Science 18:91–244.
Elliott M., Farnham, A. W., Janes, N. F. N. P. H., Pulman, D. A., and Stevenson, J. H. 1973. A Photostable Pyrethroid. Nature 246:169–170.
Everist, S. L. 1981. Poisonous Plants of Australia. London: Angus and Robertson. 966 pp.
Finnell, R. H., Gay, C. C, and Abbott, L. C. 1991. Teratogenicity of Rangeland Lupinus: the Crooked Calf Disease. In: Toxicology of Plant and Fungal Toxins — Handbook of Natural Toxins, Vol.6, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker, pp. 27–39.
Gaffield, W., and Keeler, R. F. 1994. Structure-Activity Relations of Teratogenic Natural Products. Pure and Applied Chemistry 66:2407–2410.
Gaffield, W., and Keeler, R. F. 1993. Implication of C-5, C-6 Unsaturation as a Key Structural Factor in Steroidal Alkaloid-Induced Mammalian Teratogenesis. Experientia 49:922–924.
Gaffield, W., Keeler, R. F., and Baker, D. C. 1992. Teratogenicity and Toxicity of Solanum Alkaloids. In: Natural Toxins:Toxicology, Chemistry and Safety, Keeler, R. F., Mandava, N. B., and Tu, A. T., eds. Ft. Collins, CO, Aiken Inc. pp. 18–34.
Gardner, D. R., Molyneux, R. J., James, L. F., Panter, K. E., and Stegelmeir, B. L. 1994. Ponderosa Pine Needle-Induced Abortion in Beef Cattle: Identification of Isocupressic Acid as the Principal Active Compound. Journal of Agricultural and Food Chemistry 42:756–761.
Gardner, D. R., and Panter, K. E. 1993. Comparison of Blood Plasma Alkaloid Levels in Cattle, Sheep and Goats Fed Lupinus caudatus. Journal of Natural Toxins 2:1–11.
Henrick, C. A. 1995. Pyrethroids. In: Agrochemicals From Natural Products, Godfrey, C. R. A., ed. New York, Marcel Deckker. pp. 63–146.
Hogan, M. E., and Manners, G. D. 1991. Differential Allelochemical Detoxification Mechanism in Tissue Cultures of Antenarria microphylla and Euphorbia esula. Journal of Chemical Ecology 17:167–174.
Hogan, M. E., and Manners, G. D. 1990. Allelopathy of Small Everlasting (Antennaria microphylla):Phytotoxicity to Leafy Spruge (Euphorbia esula) in Tissue Culture. Journal of Chemical Ecology 16:931–939.
Holden, C. 1989. Entomologists Wane as Insects Wax. Science 246:754–756.
Hood, R. D., and Szczech, G. M. 1983. Teratogenicity of Fungal Toxins and Fungal-Produced Antimicrobial Agents. In: Plant and Fungal Toxins–Handbook of Natural Toxins, Vol.1, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker, pp. 201–233.
Hooper, P. T. 1978. Pyrrolizidine Alkaloid Poisoning-Pathology With Particular Reference to Differences in Animal and Plant species. In: Effects of Poisonous Plants on Livestock, Keeler, R. F., Van Kamper, K. R., and James, L. F., eds. New York, Academic Press, pp. 161–176.
Huxtable, C. R. 1994. Some Characteristics of Neurones Which Endow Vulnerability to Chemical Toxins. In: Plant-Associated Toxins: Agricultural, Phytochemical and Ecological Aspects, Colegate, S. M., and Dorling, P. R., eds. Wallingford, UK, CAB International, pp. 357–362.
Inderjit, S., Dahshini, K. M. N., and Einhellig, F. A., eds. 1995. Allelopathy: Organisms, Processes and Applications,. ACS Symposium Series, 582. Washington, DC, American Chemical Society. 381 pp.
Isman, M. B. 1989. Toxicity and Fate of Acetylchromenes in Pest Insects. In: Insecticides of Plant Origin, Vol LACS Symposium Series No. 387, Arnason, J. T., Philogene, B. J. R., and Morand, P., eds. Washington, DC, American Chemical Society, pp. 44–58.
Jacobson, M. 1971. The Unsaturated Isobutylamides. In: Naturally Occurring Insecticides, Jacobson, M., and Crosby, D. G., eds. New York, Marcel Dekker, pp. 137–149.
James, L. F., Molyneux, R. J., Panter, K. E., Gardner, D. R., and Stegelmeir, B. L. 1994. Effect of Feeding Ponderosa Pine Needle Extracts and Their Residues to Pregnant Cattle. Cornell Veterinarian 84:33–39.
James, L. F., Elbein, A. D., Molyneux, R. J., and Warren, C. D.. 1989. Swainsonine and Related Glycosidase Inhibitors. Ames, Iowa: Iowa State Press. 504 pp.
James, L. F., Keeler, R. F., Johnson, A. E., Williams, M. C, Cronin, E. H., and Olsen, J. D. 1980. Plants Poisonous to Livestock in the Western United States. Agriculture Information Bulletin, 415. Washington, DC, U.S. Department of Agriculture.
James, L. F., Call, J. W., and Stevenson, A. H. 1977. Experimentally Induced Pine Needle Abortion in Range Cattle. Cornell Veterinarian 67:294–299.
Jennings, K. R., Brown, D. G., and Wright Jr., D. P. 1986. Methyllycaconitine, a Naturally Occurring Insecticide with a High Affinity for the Insect Cholinergic Receptor. Experientia (Basel) 35:611–613.
Keeler, R. F., and Tu, A. T., eds. 1991. Toxicology of Plant and Fungal Compounds–Handbook of Natural Toxins, Vol.6,. New York, Marcel Dekker.
Keeler, R. R, and Panter, K. E. 1989. Piperidine Alkaloid Composition and Relation to Crooked Calf Disease–Inducing Potential of Lupinus formosus. Teratology 40:423–432.
Keeler, R. F. 1983. Naturally Occurring Teratogens in Plants. In: Plant and Fungal Toxins–Handbook of Natural Toxins, Vol.1, Keeler, R. F., and Tu. A.T., eds. New York, Marcel Dekker, pp. 161–199.
Keeler, R. F., and Tu, A. T., eds. 1983. Plant and Fungal Toxins–Handbook of Natural Toxins, Vol.1,. New York, Marcel Dekker. 934 pp.
Keeler, R. F. 1976. Lupin Alkaloids for Teratogenic and Nonteratogenic Lupin: III. Identification of Anagyrine as the Probable Teratogen by Feeding Trials. Journal of Toxicology and Environmental Health 1:887–898.
Keeler, R. F., Young, S., and Brown D. 1976. Spina Bifida, Exencephaly, and Cranial Bleb Produced by the Solanum Alkaloid Solasodine. Research Communications in Chemistry, Pathology and Pharmacology 13:723–730.
Kingsbury, J. M. 1964. Poisonous Plants of the United States and Canada. Englewood Cliffs, N.J.: Prentice-Hall. 626 pp.
Kraus, W., Bokel, M., Schwinger, M., Bogler, B., Soellner, R., Wendisch, D., Steffens, R., and Wachendorf, U. 1993. The Chemistry of Azadirachtin and Other Insecticidal Constituents of Meliaceae. In: Phytochemistry and Agriculture, van Beek, T. A., and Breteler, H., eds. Oxford, Clarendon Press, pp. 18–39.
Larson, R. O. 1989. The Commercialization of Neem. In: Focus on Phytochemical Pesticides, Volume 1, The Neem Tree, Jacobson, M., ed. Boca Raton, FL, CRC Press, pp. 155–167.
Mann, J. 1992. Murder, Magic and Medicine. New York: Oxford University Press. 232 pp.
Manners, G. D., Panter, K. E., and Pelletier, S. W. 1995. Structure–Activity Relationships of Norditerpenoid Alkaloids Occurring in Toxic Larkspur (Delphinium) Species. Journal of Natural Products 58:863–869.
Manners, G. D., Panter, K. E., Ralphs, M. H., Pfister, J. A., Olsen, J. D., and James, L. F. 1993. Toxicity and Chemical Phenology of Norditerpenoid Alkaloids in the Tall Larkspurs (Delphinium) Species. Journal of Agricultural and Food Chemistry 41:96–100.
Manners, G. D., and Pfister, J. A. 1993. Normal Phase Liquid Chromatographic Analysis of Toxic Norditerpenoid Alkaloids. Phytochemical Analysis 4:14–18.
Manners, G. D., and Ralphs, M. H. 1989. Capillary Gas Chromatographic Analysis of Delphinium Alkaloids. Journal of Chromatography 466:427–432.
Mattocks, A. R. 1992. Recent Advances in Pyrrolizidine Research. In: Poisonous Plants, James, L. F, Keeler, R. F., Bailey Jr. E.M., Cheeke, P. R., and Hegarty, M. P., eds. Ames, Iowa, Iowa State University Press. pp. 161–168.
Mattocks, A. R. 1986. Chemistry and Toxicology of Pyrrolizidine Alkaloids. London: Academic Press–Harcourt Bruce. 393 pp.
Miyakado, M., Nakayama, I., and Ohno, N. 1989. Insecticidal Unsaturated Isobutylamides. In: Insecticides of Plant Origin, Aranason, J. T., Philogene, B. J., and Morand, P., eds. ACS Symposium Series, 387. Washington, DC, American Chemical Society, pp. 173–187.
Miyakado, M., Nakayama, I., Ohno, N., and Yoshioka, H. 1983. Structure, Chemistry and Actions of the Piperaceae Amides: New insecticidal Constituents Isolated from the Pepper Plant. In: Natural Products for Innovative Pest Management, Whitehead, D. L., and Bowers, W. S., eds. Oxford, Pergamon Press, pp. 369–384.
Molyneux, R. F. 1993a. Water Soluble Alkaloids: Cryptic Bioactive Natural Products. In: Bioactive Natural Products-Detection, Isolation and Structure Determination, Colegate, S. M., and Molyneux, R. J., eds. Boca Raton, FL, CRC Press, pp. 59–74.
Molyneux, R. J. 1993b. Toxic Range Plants and Their Constituents. In: Phytochemistry and Agriculture, van Beek, T. A., and Breteler, H., eds. Oxford, Clarendon Press, pp. 151–170.
Molyneux, R. J., and James, L. F. 1991a. Swainsonine, the Locoweed Toxin: Analysis and Distribution. In: Toxicology of Plant and Fungal Compounds-Handbook of Natural Toxins, Vol.6, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker, pp. 191–214.
Molyneux, R. J., and James, L. F. 1991b. Swainsonine, Slaframine and Castanospermine. In: Mycotoxins and Phytoalexins, Sharma, R., and Salunkhe, D. K., eds. Boca Raton, FL, CRC Press, pp. 637–656.
Moreland, D. E., and Novitzky, W. P. 1987. Effects of Phenolic Acids, Coumarins and Flavanoids on Isolated Chloroplasts and Mitochondria. In: Allelochemicals: Role in Agriculture and Forestry, Waller, G. R., ed. ACS Symposium Series, 330. Washington, DC, American Chemical Society, pp. 247–261.
Muir, A. D., Majak, W., Balza, F., and Towers, G. H. N. 1987. A Search for the Allelopathic Agents in Diffuse Knapweed. In: Allelochemical: Role in Agriculture and Forestry, Waller, G. R., ed. ACS Synposium Series, 330. Washington, DC, American Chemical Society, pp. 239–246.
Nahrstedt, A. 1993. Cyanogenesis and Foodplants. In: Phytochemistry and Agriculture, van Beek, T. A., and Breteler, H., eds. Oxford, Clarendon Press, pp. 107–129.
Nation, P. N., Benn, M. H., Roth, S. H., and Wilkens, J. L. 1982. Clinical Signs and Studies of the Site of Action of Purified Larkspur Alkaloid, Methyllycaconitine, Administered Parenterally to Calves. Canadian Veterinary Journal 23:264–266.
National Center For Health Statistics. 1991. Vital Statistics of the United States, 1988, Mortality. Part B. p. 2. Washington, DC, U.S. Public Health Service.
Naumann, K. 1990a. Chemistry of Plant Protection. Volume 4. Synthetic Pyrethroid Insecticides: Structures and Properties. Berlin: Springer-Verlag. 340 pp.
Naumann, K. 1990b. Chemistry of Plant Protection. Volume 5. Synthetic Pyrethroid Insecticides: Chemistry and Patents. Berlin: Springer-Verlag. 340 pp.
Nielsen, D. B., and James, L. F. 1992. The Economic Impacts of Livestock Poisonings by Plants. In: Poisonous Plants, James, L. F., Keeler, R. F., Bailey Jr., E. M., Cheeke, P. R., and Hegarty, M. P., eds. Ames, Iowa, Iowa State University Press, pp. 3–10.
Nielsen, D. B., and Ralphs, M. H. 1988. Larkspur, Economic Considerations. In: The Ecology? and Economic Impact of Poisonous Plants on Livestock Production, James, L. F., Ralphs, M. H., and Nielsen, D. B., eds. Boulder, CO, Westview Press, pp. 119–129.
Offterdinger, H., and Weger, N. 1969. Circulation and Respiration in Cyanide Poisoning and its Therapy with Ferrihemoglobin and Cobalt Containing Agents. Archives of Experimental Pathology and Pharmacology 264:289–294.
Olden, K., White, S. L., Newton, S. A., Molyneux, R. J., and Humphries, M. J. 1991. Antineoplastic Potential and Other Possible Uses of Swainsonine and Related Compounds. In: Toxicology of Plant and Fungal Compounds — Handbook of Natural Toxins, Vol.6, Keeler, R. F., Tu, A. T., eds. New York, Marcel Dekker, pp. 575–588.
Olsen, J. D. 1978. Tall Larkspur Poisoning in Cattle and Sheep. Journal of the American Veterinary Medical Association 173:762–765.
Panter, K. E. 1993. Ultrasound Imaging: a Bioassay Technique to Monitor Fetotoxity of Natural Toxicants and Teratogens. In: Bioactive Natural Products: Detection, Isolation and Structural Determination, Colegate, S. M., and Molyneux, R. J., eds. Boca Raton, CRC Press, pp. 465–480.
Panter, K. E., Ralphs, M. H., Smart, R. A., and Duelke, B. 1987. Death Camas Poisoning in Sheep: a Case Report. Veterinary and Human Toxicology 29:45–48.
Parsons, J. A. 1965. A Digitalis-like Toxin in the Monarch Butterfly Danaus plexippus L. Journal of Physiology 178:290–304.
Pelletier, S. W., and Joshi, B. S. 1991. Carbon-13 and Proton NMR Shift Assignments and Physical Constants of Norditerpenoid Alkaloids. In: Alkaloids: Chemical and Biological Perspectives, Vol.7, Pelletier, S. W., ed. New York, Springer-Verlag, pp. 297–564.
Pelletier, S. W., Mody, N. V, Joshi, B. S., and Schramm, L. C. 1984. Carbon-13 and Proton NMR Shift Assignments and Physical Constants of C19–Diterpenoid Alkaloids. In: Alkaloids: Chemical and Biological Perspectives, Vol.2, Pelletier, S. W., ed. New York, Wiley & Sons. pp. 205–462.
Pelletier, S. W., Dailey Jr., O. D., Mody, N. V, and Olsen, J. D. 1981. Isolation and Structure Elucidation of the Alkaloids ofDelphinium glaucescens Rybd. Journal of Organic Chemistry 46:3284–3293.
Peterson, J. E., and Culvenor, C. C. J. 1983. Hepatotoxic Pyrrolizidine Alkaloids. In: Plant and Fungal Toxins-Handbook of Natural Toxins, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker. pp. 637–671.
Pfister, J. A., Manners, G. D., Gardner, D. R., and Ralphs, M. H. 1994a. Toxic Alkaloid Levels in Tall Larkspur (Delphinium barbeyi) in Western Colorado. Journal of Range Management Al:355–358.
Pfister, J. A., Panter, K. E., Manners, G. D., and Cheney, C. D. 1994b. Reversal of Tall Larkspur (Delphinium barbeyi) Poisoning in Cattle With Physostigmine. Veterinary and Human Toxicology 36:511–514.
Poulton, J. E. 1990. Cyanogenesis in Plants. Plant Physiology 94:401–411.
Poulton, J. E. 1988a. Localization and Catabolism of Cyanogenic Glycosides. In: Cyanide Compounds in Biology, Vol. 140, CIBA Foundation, eds. Chichester, Wiley. 261 pp.
Poulton, J. E. 1988b. Toxic Compounds in Plant Foodstuffs:Cyanogens. Food Proteins 381–401.
Poulton, J. E. 1983. Cyanogenic Compounds in Plants and Their Toxic Effects. In: Plant and Fungal Toxins-Handbook of Natural Toxins, Vol. 1, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker. pp.117–157.
Putnam, A. R., T. S. Tang, and eds. 1986. The Science of Allelopathy. New York: John Wiley and Sons. 317 pp.
Reichstein, T., von Euw, J., Parsons, J. A., and Rothschild, M. 1968. Heart Poisons in the Monarch Butterfly. Science 161:861–866.
Rembold, H. 1989a. In: Focus on Phytochemical Pesticides, Volume 1, The Neem Tree, Jacobsen, M., ed. Boca Raton, FL, CRC Press, pp. 19–34.
Rembold, H. 1989b. Azadirachtins: Their Structure and Mode of Action. In: Insecticides of Plant Origin, Arnason, J. T., Philogene, B. F. R., and Morand, P., eds. ACS Symposium Series, 387. Washington, DC, American Chemical Society, pp. 150–163.
Rice, E. L. 1984. Allelopathy. New York: Academic Press. 357 pp.
Ripperger, H., and Schreiber, K. 1981. Solanum Steroid Alkaloids. In: The Alkaloids–Chemistry and Physiology, Vol.19, Manske, R. H. F., ed. pp. 81 – 192 New York, Academic Press.
Roeske, C. N., Seiber, J. N., Brower, L. P., and Moffitt, C. M. 1976. Milkweed Cardenolides and Their Comparative Processing by Monarch Butterflies Danaus plexippus L. Recent Advances in Phytochemistry 10:93–167.
Roitman, J. N., and Panter, K. E. 1995. Livestock Poisoning Caused by Plant Alkaloids. In: Toxic Action of Marine and Terrestial Alkaloids, Blum, M.S. ed. Fort Collins, CA, Alaken, Inc. pp 53–124.
Roitman, J. N. 1981. Comfrey and Liver Damage. The Lancet ii:944.
Rothschild, M., and Marsh, C. D. 1978. Some Peculiar Aspects of Danaid/Plant Relationships. Entomological Experimentation and Application 24:437–450.
Ruigt, G. S. F. 1985. Pyrethroids. In: Conprehensive Insect Physiology, Biochemistry and Pharmacology, Vol.12, Dekut, G. A., and Gilbert, L. I., eds. Oxford, UK, Pergamon. pp. 183–262.
Schmutterer, H. 1990. Properties and Potential of Natural Pesticides from the Neem Tree, Azadirachta indica. In: Annual Review of Entomology, Vol.35, Mittler, T. E., Radovsky, F. J., and Resh, V. H., eds. Palo Alto, Annual Reviews Inc. pp. 271–297.
Seiber, J. N., Lee, S. M., and Benson, J. M. 1983. Cardiac Glycosides (Cardenolides) in Species of Asclepias (Asclepiadaceae). In: Plant and Fungal Toxins-Handbook of Natural Toxins, Vol.1, Keeler, R. F., and Tu, A. T., eds. New York, Marcel Dekker, pp. 43–83.
Seiber, J. N., Nelson, C. J., and Benson, J. M. 1980. Pharmacodynamics of Some Individual Milkweed Cardenolides Fed to Larvae of the Monarch Butterfly. Journal of Chemical Ecology 8:321–339.
Seigier, D. S. Cyanide and Cyanogenic Glycosides. 1991. In: Herbivores: Their Interactions with Secondary Plant Metabolites. The Chemical Participants, Vol.1, Rosenthal, G. A., and Berenbaum, M. R., eds. San Diego, Academic Press, pp. 35–77.
Severson, R. F., Arrendale, R. F., Cutler, H. G., Jones, D., Sisson, V. A., and Stephenson, M. G. 1988. Chemistry and Biological Activity of Acylnornicotines from Nicotiana repandae. In: Biologically Active Natural Products, Potential Use in Agriculture, Cutler, H. G., edACS Symposium Series, 335. Washington, DC, American Chemical Society.. pp. 335–362.
Shettel, N., and Balke, N. E. 1983. Plant Growth Response to Several Allelopathic Chemicals. Weed Science 31:293–298.
Shull, L. R., Buchmaster, G. W., and Cheeke, P. R. 1976. Factors Influencing Pyrrolizidine (Senecio) Alkaloid Metabolism: Species, Liver Sulfhydryls and Rumen Fermentation. Journal of Animal Science 43:1247–1253.
Shupe, J. L., Binns, W., James, L. F., and Keeler, R. F. 1968. A Congenital Deformity in Calves Induced by the Maternal Consumption of Lupine. Australian Journal of Agricultural Research 19:335–340.
Shupe, J. L., Binns, W, James, L. F, and Keeler, R. F. 1967. Lupine, a Cause of Crooked Calf Disease. Journal of the American Veterinary Medical Association 43:1247–1253.
Soderlund, D. M., and Bloomquist, J. R. 1989. Neurotoxic Actions of Pyrethroid Insecticides. In: Annual Reviews of Entomology, Vol.34, Mittler, T. E., Radovsky, F. J., and Resh, V. H., ed. Palo Alto, USA, Annual Reviews Inc. pp. 77–96.
Staal, G. B. 1986. Anti Juvenile Hormone Agents. In: Annual Review of Entomology, Vol.31, Mittler, T. E., Radovsky, F. J., and Resh, V. H., eds. pp. 391 – 429 Palo Alto, Annual Reviews Inc.
Staal, G. B. 1986. Anti Juvenile Hormone Agents. In: Annual Review of Entomology, Vol.31, Mittler, T. E., Radovsky, F. J., and Resh, V. H., eds. pp. 391 – 429 Palo Alto, Annual Reviews Inc.
Stevens, K. L. 1986. Allelopathic Polyacetylenes From Centaurea repens (Russian Knapweed). Journal of Chemical Ecology 12:1205–1211.
Tang, T. S., and Zhang, B. 1986. Qualitative and Quantitative Determination of the Allelochemical Sphere of Germinating Mung Bean. In: The Science of Allelopathy, Putnam, A. R., and Tang, C. S., eds. New York, John Wiley and Sons, pp. 229–242.
Thompson, A. C, ed. 1985. The Chemistry of Allelopathy,. ACS Symposium Series, 286. Washington, DC, American Chemical Society. 470pp.
von Euw, J., Fishelson, L., Parsons J.A., Reichstein, T., and Rothschild, M. 1967. Cardenolides (Heart Poisons) in a Grasshopper Feeding on Milkweeds. Nature (Lond.) 214:35–39.
Waller, G. R., ed. 1987. Allelochemical: Role in Agriculture and Forestry,. ACS Symposium Series, 330. Washington, DC, American Chemical Society. 660 pp.
Weston, L. A., Burke, B. A., and Putnam, A. R. 1987. Isolation Characterization and Activity of Phytotoxic Compounds from Quackgrass (Agropyron repens (L.)Beauv.). Journal of Chemical Ecology 13:403–421.
Whitman, D. W. 1988. Allelochemical Interactions Among Plants, Herbivores and Their Predators. In: Novel Aspects of Insect–Plant Interactions, Barbosa, P., and Letourneau, D. K., eds. pp. 11 – 64 New York, Wiley-Interscience.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Plenum Press, New York
About this chapter
Cite this chapter
Manners, G.D. (1996). Plant Toxins. In: Singh, B.R., Tu, A.T. (eds) Natural Toxins 2. Advances in Experimental Medicine and Biology, vol 391. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0361-9_2
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0361-9_2
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4613-8016-0
Online ISBN: 978-1-4613-0361-9
eBook Packages: Springer Book Archive