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Tumour Suppressor Genes in Hodgkin’s Disease

  • Chapter
Etiology of Hodgkin’s Disease

Abstract

Molecular studies of neoplastic transformation are uncovering a process involving an accumulation of genetic alterations in the initiation and progression of neoplasia. These include oncogene activation leading to growth promotion, and the inactivation of the so-called tumour suppressor genes (TSG) resulting in loss of the growth suppressor effect.

This work was made possible by grants 92/0721 and 93/0016, from the Fondo de Investigacion Sanitaria (FIS), Spain.

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Piris, M.A. et al. (1995). Tumour Suppressor Genes in Hodgkin’s Disease. In: Jarrett, R.F. (eds) Etiology of Hodgkin’s Disease. NATO ASI Series, vol 280. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0339-8_17

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