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Clinical presentation and management of patients with circulating anticoagulants

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Inhibitors to Coagulation Factors

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 386))

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Abstract

Acquired hemophilia is characterized by the development of antibodies to coagulation proteins. Although these inhibitors are rare, they pose serious threats to health as a result of their ability to produce spontaneous hemorrhage. As these inhibitors occur infrequently, epidemiological analyses of their patterns of occurrence, details of clinical presentations, and practical management of acute hemorrhage are difficult to gather. In an effort to augment the clinical data base, we reviewed the records of 26 patients treated at our institution from 1980 to 1993.

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References

  1. . Green, D., and Lechner, K., A survey of 215 non-hemophilic patients with inhibitors to Factor VIII, Thromb Haemost. 45: 200 (1981).

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© 1995 Plenum Press, New York

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Moliterno, A., Bell, W.R. (1995). Clinical presentation and management of patients with circulating anticoagulants. In: Aledort, L.M., Hoyer, L.W., Lusher, J.M., Reisner, H.M., White, G.C. (eds) Inhibitors to Coagulation Factors. Advances in Experimental Medicine and Biology, vol 386. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-0331-2_13

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  • DOI: https://doi.org/10.1007/978-1-4613-0331-2_13

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-8001-6

  • Online ISBN: 978-1-4613-0331-2

  • eBook Packages: Springer Book Archive

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