Cloning and Expression of the Gene Encoding a Novel Proteinase from TritiraChium Album Limber

  • Babru Sama
  • Tom Boone
  • Barbara Karan
  • Kenneth Chen
  • Raj Sachdev
  • Tsutomo Arakawa
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 379)


We have isolated the cDNA and the genomic clones encoding a novel serine proteinase, named proteinase T, from the fungus Tritirachium album Limber. The coding region of the gene is interrupted by two introns. The amino acid sequence of proteinase T as deduced from the nucleotide sequence is about 56% identical to that of proteinase K. Four cysteines are present in the mature proteinase, probably in the form of disulfide bonds.


Mature Proteinase Tritirachium Album 
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Copyright information

© Plenum Press, New York 1996

Authors and Affiliations

  • Babru Sama
    • 1
  • Tom Boone
    • 1
  • Barbara Karan
    • 1
  • Kenneth Chen
    • 1
  • Raj Sachdev
    • 1
  • Tsutomo Arakawa
    • 1
  1. 1.Amgen CenterAmgen Inc.USA

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