Abstract
For the past three decades, individuals and organizations that conduct clinical trials have struggled to increase patient enrollment. As the number of patients required for the average clinical trial has increased, recruitment has become the primary obstacle to fast, efficient trial completion, consuming close to 30% of clinical development time. To expedite trials, we must identify the factors that complicate patient recruitment and implement solutions like improved trial design and e-enabled enrollment. In this chapter, we explore our progress to date, summarizing research on clinical trial participation and describing current efforts to solve the recruitment problem.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Albrecht TL, Blanchard C, Ruckdeschal JC, Coovert M, Strongbow R. 1999. Strategic Physician Communication and Oncology Clinical Trials. J Clin Oncol 17(10):3324–3332.
Ellis PM, Butow PN, Simes RJ, TaHersall MH, Dunn SM. 1999. Barriers to Participation in Randomized Clinical Trials for Early Breast Cancer Among Australian Cancer Specialists. Aust N Z J Surg 69(7):486–491.
Emanuel E. 1999. Presidential Symposium: Report of the Clinical Trials Subcommittee. ASCO Virtual Meeting, http://www.conference-cast.com/asco/default_vm99.htm.
Hjorth M, Holmberg E, Rodjer S, Taube A, Westin J. 1996. Physicians’ Attitudes Toward Clinical Trials and Their Relationship to Patient Accrual in a Nordic Multicenter Study on Melanoma. Control Clin Trials 17(5):372–386.
Lutz S, Henkind SJ. 2000. Recruiting for Clinical Trials on the Web. Healthplan 2000 41(5):36–43.
McCaskill-Stevens W, Pinto H, Marcus AC, Comis R, Morgan R, Plomer K, Schoentgen S. 1999. Recruiting Minority Cancer Patients into Cancer Clinical Trials: A Pilot Project Involving the Eastern Cooperative Oncology Group and the National Medical Association. J Clin Oncol 17(3): 1029–1039.
Schnipper L. 1999. Presidential Symposium: Report of the Clinical Trials Subcommittee. ASCO Virtual Meeting, http://www.conference-cast.com/asco/default_vm99.htm.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer Science+Business Media New York
About this chapter
Cite this chapter
Glodé, L.M. (2002). Clinical Trials in Practice. In: Silva, J.S., et al. Cancer Informatics. Health Informatics. Springer, New York, NY. https://doi.org/10.1007/978-1-4613-0063-2_4
Download citation
DOI: https://doi.org/10.1007/978-1-4613-0063-2_4
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-6547-4
Online ISBN: 978-1-4613-0063-2
eBook Packages: Springer Book Archive