The cardiovascular system has to supply all organs with blood according to their metabolic requirements and functions. The three main factors—blood flow, arterial blood pressure, and arterial Po2—are of varying importance in different organs. If metabolism and function run more or less parallel, as in the brain, liver, and muscles, both a deficient blood flow and a fall of the arterial Po2 lead to functional impairment. On the other hand, if oxygen consumption is small in comparison with blood flow, as in the kidney, normal function depends primarily on the blood flow and the arterial pressure and is only minimally susceptible to hypoxemia.
KeywordsCardiac Output Stroke Volume Pulmonary Arterial Hypertension Myocardial Blood Flow Atrial Septal Defect
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