Discussion/Chapters 10–12

  • Volker ter Meulen
  • Michael Katz
Conference paper


Dr. Askonas began by asking Dr. Norrby whether the monoclonal antibodies were directed against certain viral fractions, perhaps the intracellular ones. Dr. Norrby responded that this has not yet been studied, but that in his studies he used virus antigens produced in the cell culture system and absorbed with intracellular and extracellular virus, but not with the cell material itself. The interesting thing, he continued, was the remarkable persistence of the individual clones, which remained relatively constant within each patient, even as there is considerable variation among patients.


Multiple Sclerosis Multiple Sclerosis Patient Virus Antigen Cell Culture System Individual Clone 
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Copyright information

© Springer Science+Business Media New York 1977

Authors and Affiliations

  • Volker ter Meulen
    • 1
  • Michael Katz
    • 2
  1. 1.Institut fuer VirologieWuerzburgWest Germany
  2. 2.College of Physicians and SurgeonsColumbia UniversityNew YorkUSA

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