Glucagon-Like Materials in Porcine and Rat Intestinal Mucosa

  • J. M. Conlon
  • K. D. Buchanan
  • R. F. Murphy
Conference paper

Abstract

Extracts of gastrointestinal tissue contain glucagon-like immunoreactive (GLI) materials with molecular weights varying between 2000 and 30,000. Some of them react with antisera specific for the C-terminal, others with antisera specific for the N-terminal portion of the glucagon molecule. In response to perfusion with glucose the serosal surface of rat small intestine releases increased amounts of some GLI fractions.

Keywords

Bromide Electrophoresis Polypeptide Polyacrylamide Dodecyl 

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Copyright information

© Springer-Verlag New York Inc. 1977

Authors and Affiliations

  • J. M. Conlon
    • 1
    • 2
  • K. D. Buchanan
    • 1
    • 2
  • R. F. Murphy
    • 1
    • 2
  1. 1.Department of BiochemistryQueen’s University of BelfastBelfastNorthern Ireland
  2. 2.Department of MedicineQueen’s University of BelfastBelfastNorthern Ireland

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