Relationship between rCBF changes and restitution of neurologic, psychopathologic, and electroencephalographic disturbances in patients with occlusion of middle cerebral artery and internal carotid artery

  • H. Herrschaft


Global (gCBF) and regional cerebral blood flow (rCBF) measurements in patients with total or partial occlusion of the middle cerebral artery (MCA) have been performed since 1965 in greater numbers and under varying clinical-experimental conditions. The authors, however, reported in mutual agreement that, upon occurrence of stroke following MCA occlusion within the first 3 days, an ischemic focus, accompanied as a rule by a global diminution of the blood flow within the corresponding hemisphere, had formed in most cases.(1,2,5–8,12–14,16–19) In rare cases, however, a hyperemic focus had been observed within the first 2-day period.(3,4,11,19)


Cerebral Blood Flow Internal Carotid Artery Middle Cerebral Artery Motor Deficit Regional Cerebral Blood Flow 
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  1. 1.
    Agnoli A, Battistini N, Bozzao L, Fieschi C: Derangement de l’Autoregulation dans les Foyers Ischemiques Cérébraux: Possibilités Terapeutiques au moyen des Medicaments Hypertenseurs. Symposium International sur la Circulation Cérébrale. Paris, Sandoz 1965, p 114Google Scholar
  2. 2.
    Agnoli A, Fieschi C, Bozzao L, Battistini N, Prencipe N: Autoregulation of cerebral blood flow studies during drug-induced hypertension in normal subjects and in patients with cerebral vascular diseases. Circulation 38: 800, 1968PubMedGoogle Scholar
  3. 3.
    Cronqvist S: Transitory hyperaemia in focal cerebral ischemic lesions. III. In Lechner H., Eichhorn O (eds): International Symposium on Cerebral Circulation, Salzburg 1969. Springfield Ill, Thomas, 1969, p 71Google Scholar
  4. 4.
    Cronqvist S, Laroche F: Transitory hyperemia in focal cerebral vascular lesions, studied by angiography and regional cerebral blood flow measurements. Br J Radiol 40: 270, 1967PubMedCrossRefGoogle Scholar
  5. 5.
    Ekberg R, Cronqvist S, Ingvar DH: Regional cerebral blood flow in cerebrovascular disease. Acta Neurol Scand Suppl 14: 164, 1965PubMedGoogle Scholar
  6. 6.
    Fieschi C, Agnoli A, Battistini N, Bozzao L: Regional cerebral blood flow in patients with brain infarcts: A study with the 85 Kr clearance technique. Arch Neurol 15: 653, 1966PubMedGoogle Scholar
  7. 7.
    Herrschaft H: Die regionale Gehirndurchblutung. Berlin Heidelberg New York, Springer-Verlag, 1975, pp 140–167Google Scholar
  8. 8.
    Herrschaft H: Die quantitative Messung der örtlichen Hirndurchblutung. Ihre Bedeutung für die Diagnostik und Therapie der cerebralen Durchblutungsstörungen. Habilitationsschrift. Frankfurt/Main, 1972Google Scholar
  9. 9.
    Herrschaft H: Die quantitative Messung der örtlichen Hirndurchblutung beim Menschen. Herz/Kreislauf 6: 220, 1974Google Scholar
  10. 10.
    Herrschaft H: Gehirndurchblutung und Gehirnstoffwechsel. Stuttgart, Thieme, 1976Google Scholar
  11. 11.
    Hjöedt-Rasmussen K, Skinhjoj E, Paulson O, Ewald J, Bjerrum JK, Fahrenkrug A, Lassen NA: Regional cerebral blood flow in acute apoplexy. The luxury perfusion syndrome of brain tissue. Arch Neurol 17: 271, 1967Google Scholar
  12. 12.
    Jaffe ME, McHenry LC, Goldberg HI: Regional cerebral blood flow measurements with small probes. II. Clinical application of the method. Neurology 20: 25, 1970Google Scholar
  13. 13.
    Kempinsky WH, Boniface WR, Keating JBA: Serial hemodynamic, study of cerebral infarction in man. Circ Res 9: 1051, 1961PubMedGoogle Scholar
  14. 14.
    McHenry LC: Cerebral blood flow studies in middle cerebral and cortical artery occlusion. Neurology 126 (12): 1145, 1966Google Scholar
  15. 15.
    Meyer JSt, Kanda T, Fukuuchi Y, Shimazu S, Dennis EW, Ericsson AD: Clinical prognosis correlated with hemispheric blood flow in cerebral infarction. Stroke 2: 383, 1971CrossRefGoogle Scholar
  16. 16.
    Paulson OB: Regional cerebral blood flow in middle cerebral artery occlusion. Scand J Clin Lab Invest (Suppl 102) XVI:C, 1968Google Scholar
  17. 17.
    Paulson OB: Regional cerebral blood flow at rest and during func-tional tests in occlusive and nonocclusive cerebrovascular disease. In Brock M, Fieschi C, Ingvar DH, Lassen NA, Schürmann K (eds): Cerebral Blood Flow. Berlin Heidelberg New York, Springer-Verlag 1969, p 111Google Scholar
  18. 18.
    Paulson OB: Regional cerebral blood flow studies in various types of cerebrovascular disease. In Meyer JSt, Lechner H, Reivich M, Eichhorn O (eds): Research on the Cerebral Circulation. Fourth International Salzburg Conference, Springfield, Ill, Thomas, 1970Google Scholar
  19. 19.
    Paulson OB: Regional cerebral blood flow in apoplexy due to occlusion of the middle cerebral artery. Neurology 20: 63, 1970PubMedGoogle Scholar
  20. 20.
    Zülch KJ: Zentrale Störungen der Motorik und ihre Restitution nach dem Prädilektionstyp von Wernicke-Mann. Dtsch Z Nervenheilkd 175: 217, 1956PubMedCrossRefGoogle Scholar
  21. 21.
    Zülch KJ: Traumatische Störungen der Motorik und Sensibilität und ihre Restitution. Dtsch Z Nevenheilkd 166: 400, 1951Google Scholar
  22. 22.
    Zülch, KJ, Müller N: Associated movements in man. In Vinken PJ, Bruyn GW (eds): Handbook of Clinical Neurology, Amsterdam, North-Holland, 1969, Vol I, Chap 14Google Scholar

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© Springer-Verlag New York Inc. 1977

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  • H. Herrschaft

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