Hormonal Influences on Erythroid Colony Growth in Culture

  • John W. Adamson
  • William J. Popovic
  • James E. Brown


The growth and function of a number of cellular systems are influenced by interactions of different hormones and small molecules.1,2,3 Several studies have shown that a variety of hormones, incapable of initiating a metabolic event or differentiative function by themselves, have the capacity to enhance the effect of primary regulatory hormones. As an example, dibutyryl cyclic adenosine monophosphate (db-cAMP) enhances the induction of tyrosine aminotransferase in cultured hepatoma cells, but only in the presence of or following preconditioning of the cells by a glucocorticoid such as dexamethasone.4


Thyroid Hormone Velocity Sedimentation Colony Growth Colony Number Control Coloni 
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Copyright information

© Springer-Verlag New York Inc. 1978

Authors and Affiliations

  • John W. Adamson
  • William J. Popovic
  • James E. Brown

There are no affiliations available

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