Interest in coat-color genetics is almost as old as the science of genetics itself, for it was only shortly after the rebirth of Mendelism, at the beginning of the century, that W.E. Castle and his students, as well as others, initiated studies on the inheritance of specific coat colors in guinea pigs, rats, rabbits, and mice. Although these investigators were completely unaware of the anatomical basis of pigmentation, not to mention its biochemistry, their studies clearly established that the production of coat-color patterns involved a local interaction of specific gene products which was relatively unaffected by systemic or environmental factors.
KeywordsNeural Crest Pigment Granule Medullary Cell Melanin Granule Hair Bulb
Unable to display preview. Download preview PDF.