Morphologic and Functional Correlates in Transient Cerebral Ischemia
As the two extreme entities of clinical cerebral ischemia, we have transient cerebral ischemia (TIA) on the one side and the completed stroke syndrome (CS) on the other. The essential criterion for this classification, which also includes various other terms such as prolonged reversible cerebral ischemia (PRIND) and progressive stroke (PS), is based on the temporal profile of presenting neurologic symptoms following an ischemic event in the brain. Thus, in a completed stroke the resulting neurologic deficit is more or less definite and represents a stabilized condition. It is generally accepted and well documented in the literature, particularly since the introduction of CT scanning, that a completed stroke is associated with irreversible structural damage of the brain tissue.1, 4 In contrast to this, the complete reversibility of neurologic symptoms within 24 hours, which by definition is characteristic of transient cerebral ischemia, would, at least theoretically, imply that there are no lasting functional or structural sequelae detectable within the brain beyond the given time period after an attack.
KeywordsCerebral Ischemia Regional Cerebral Blood Flow Cerebral Angiography Carotid Artery Occlusion Transient Cerebral Ischemia
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