Abstract
The question explored in this brief discussion is as follows: what are the nascent lipoproteins synthesized and secreted by normal rat liver?
This work was supported by the U.S. Public Health Service, Arteriosclerosis SCOR grant HL 14237.
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References
Alexander CA, Hamilton RL, Havel RJ (1976) Subcellular localization of B apo-protein of plasma lipoproteins in rat liver. J Cell Biol 69: 241–263
Chajek T, Fielding CJ (1979) Isolation and characterization of a human serum cholesteryl ester transfer protein. Proc Natl Acad Sci USA 75: 3445–3449
Forte T, Norum KR, Glomset JA, Nichols AV (1971) Plasma lipoproteins in familial lecithin: cholesterol acyltransferase deficiency: structure of low and high density lipoproteins as revealed by electron microscopy. J Clin Invest 50: 1141–1148
Hamilton RL (1972) Synthesis and secretion of plasma lipoproteins. In: Holmes WL, Paoletti R, Kritchevsky D (eds) Pharmacological Control of Lipid Metabolism (Adv Exp Med Biol). Plenum, New York, pp 7–24
Hamilton RL (1978) Hepatic secretion and metabolism of high density lipoproteins. In: Dietschy JM, Gotto AM, Ontko JA (eds) Disturbances in Lipid and Lipoprotein Metabolism. American Physiological Society, Bethesda, pp 155–171
Hamilton RL, Kayden HJ (1974) The liver: Normal and abnormal functions. In: Becker FF (ed) The Liver and the Formation of Normal and Abnormal Plasma Lipoproteins. Dekker, New York, Vol 5, Part A, pp 531–572
Hamilton RL, Williams MC, Fielding CJ, Havel RJ (1976) Discoidal bilayer structure of nascent high density lipoproteins from perfused rat liver. J Clin Invest 58: 667–680
Havel RJ (1978) Origin of HDL. In: Gotto AM, Miller NE, Oliver MF (eds) High Density Lipoproteins and Atherosclerosis. Elsevier Press, Amsterdam
Jona A (1979) Interaction of bovine serum high density lipoprotein with mixed vesicles of phosphatidylcholine and cholesterol. J Lipid Res 20: 817–824
Mahley RW, Hamilton RL, LeQuire VS (1969) Characterization of lipoprotein particles isolated from the Golgi apparatus of rat liver. J Lipid Res 10: 433–439
Marsh JB (1976) Apoproteins of the lipoproteins in a nonrecirculating per-fusate of rat liver. J Lipid Res 17: 85–90
Morré DJ, Hamilton RL, Mollenhauer HH, Mahley RW, Cunningham WP, Cheetham RD, LeQuire VS (1970) Isolation of a Golgi apparatus-rich fraction from rat liver. J Cell Biol 44: 484–491
Nichols AV, Gong EL, Forte TM, Blanche PJ (1978) Interaction of plasma high density lipoprotein HDL2b (d 1.063-1.100 gm/ml) with single bilayer liposomes of dimyristoylphosphatidylcholine. Lipids 13: 943–950
Patsch JR, Gotto AM, Olivecrona T, Eisenber S (1978) Formation of highdensity Iipoprotein2-like particles during lypolysis of very low density lipoprotein in vitro. Proc Natl Acad Sci USA 75: 4519–4523
Redgrave TG, Small DM (1979) Quantitation of the transfer of surface phos-pholipid of chylomicrons to the high density lipoprotein fraction during the catabolism of chylomicrons in the rat. J Clin Invest 64: 162–171
Tall AR, Small DM (1978) Plasma high-density lipoproteins. N Engl J Med 299: 1232–1236
Torsvik H, Solaas MH, Gjon E (1970) Serum lipoproteins in plasma lecithin cholesterol acyltransferase deficiency, studied by electron microscopy. Clin Genet 1: 139–150
Windmueller EG, Levy RI (1967) Total inhibition of hepatic 3-lipoprotein production in the rat by orotic acid. J Biol Chem 242: 2246–2254
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Hamilton, R.L. (1980). Nascent VLDL and Nascent HDL from Liver. In: Gotto, A.M., Smith, L.C., Allen, B. (eds) Atherosclerosis V. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-6071-4_35
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DOI: https://doi.org/10.1007/978-1-4612-6071-4_35
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