Is Long-Term Antithyroid Drug Therapy for Graves’ Disease Cost-Effective?

  • Joel I. Hamburger


Antithyroid drugs (ATD) have been employed for the treatment of hyperthyroidism (principally Graves’ disease) since the 1940s. ATD treatment will be followed by remission in the hyperthyroidism for some patients. Initially good results were claimed for 50–70% of patients.1,2 Recently success has been achieved in 15–30%,3–5 excepting the unique report of Slingerland and Burrows6 in which a 76% remission rate is claimed after prolonged treatment. Favorable candidates for ATD are young, have small goiters or goiters which regress during treatment, and have mild hyperthyroidism of short duration.1,5,7,8


Radioactive Iodine Veteran Administration Sustained Remission Hyperthyroid Patient Subtotal Thyroidectomy 
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© Springer-Verlag New York Inc. 1981

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  • Joel I. Hamburger

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