Position Paper: The Concept of Whole Body Autoregulation and the Dominant Role of the Kidneys for Long-term Blood Pressure Regulation

  • Arthur C. Guyton
  • John E. Hall
  • Thomas E. Lohmeier
  • R. Davis ManningJr.
  • Thomas E. Jackson


This paper addresses two different topics: a) the concept of whole body autoregulation; and b) the role of the kidneys for long-term blood pressure regulation. In the minds of most persons in the field of hypertension research, these are interdependent phenomena. However, this is quite untrue. One of the purposes of this paper will be to point out the independence of these two phenomena, to show that each one of them can function independently of the other—though, at times, they do function together.


Cardiac Output Arterial Pressure Equilibrium Point Total Peripheral Resistance Local Blood Flow 
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Copyright information

© Springer-Verlag New York Inc. 1981

Authors and Affiliations

  • Arthur C. Guyton
  • John E. Hall
  • Thomas E. Lohmeier
  • R. Davis ManningJr.
  • Thomas E. Jackson

There are no affiliations available

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