Sodium and Other Dietary Factors in Experimental and Human Hypertension: The Japanese Experience
Stroke is the most preponderant cause of death in Japan, while myocardial infarction is the first cause of death in Western countries. Epidemiologic studies have indicated that stroke incidence in Japan, which is closely related to hypertension itself, is rather inversely correlated with serum cholesterol levels that are generally far lower than those of the populations in Western countries; the mean of the various populations in Japan is mostly below 200 mg/dl. Since the stroke incidence is higher in rural inhabitants in Japan who are taking less cholesterol and protein, but excess salt (the mean daily intake is mostly over 12 g, not infrequently over 20 g), salt excess seems to be more closely related to high stroke incidence.
KeywordsProtein Intake Stroke Incidence Salt Sensitivity Rural Inhabitant Human Hypertension
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