Abstract
Gastrointestinal disorder related to drug administration is a common phenomenon (1–6). In one study, drug reactions occurred in 16% of all hospital inpatients, with gastrointestinal reactions accounting for 26.9% of the total (1). Although frequently the reaction may be minor, such as mild nausea, vomiting, or diarrhea, serious drug-induced disease is often encountered as well. Outpatient illness serious enough to warrant medical service admission included 2.9% drug-induced cases in one series, excluding suicide attempts and drug abuse (5). Gastrointestinal reactions, usually hemorrhage, were the second most common manifestation (18.5%) after cardiovascular (22.2%).
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References
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Hyson, E.A., Burrell, M., Toffler, R. (1981). Drug-Induced Gastrointestinal Disorders. In: Iatrogenic Gastrointestinal Complications. Radiology of Iatrogenic Disorders. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5853-7_1
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