Abstract
The standard laboratory procedures involved in cytogenetics for clinical evaluation or for screening potential clastogens and exposed personnel are time-consuming, costly, and by their nature, self-limiting in terms of volume production. The rapid developments in computer technology, especially in pattern recognition, provided a possible solution to the problems in processing and analyzing specimens. Several independent methodologies were developed during the period 1965–78 (Mendelsohn, 1976) for automated karyotyping. A recent workshop on automated human cytogenetics held in Copenhagen abstracted the projects in progress in Europe (Granum and Jakobsen, 1978).
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References
Castleman, K.R., Melnyk, J., Frieden, HJ., Persinger, G.W., Wall, R.J. (1976): Karyotype analysis by computer and its application to mutagenicity testing of environmental chemicals. Mutat. Res. 41: 153–162.
Granum, E., Jakobsen, B. (eds.) (1978): Proceedings of the 1978 Workshop in Automated Human Cytogenetics. Copenhagen, The Technical University of Denmark.
Mendelsohn, M. (1976): Introduction. In: M. Mendelsohn (ed.), Automation of Cytogenetics: Asilomar Workshop. Springfield, Virginia, National Technical Information Service, pp. 1–2.
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© 1981 Springer-Verlag New York Inc.
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Melnyk, J., Castleman, K.R., Persinger, G.W. (1981). Automation in Cytogenetics. In: Stich, H.F., San, R.H.C. (eds) Short-Term Tests for Chemical Carcinogens. Topics in Environmental Physiology and Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5847-6_23
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DOI: https://doi.org/10.1007/978-1-4612-5847-6_23
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