Abstract
Excess absorbed Cu is excreted in bile as a poorly absorbed macromolecular complex (1). We recently provided evidence of a reversible abnormality of biliary Cu excretion in chronic pancreatitis (2): after secretin biliary Cu was higher in nontreated patients than controls but lower in patients on long-term treatment with pancreatic extracts. These results suggested that a constituent of pancreatic juice in pancreatic extracts limits Cu absorption and thereby assists bile in maintaining Cu homeostasis. Support for this hypothesis is presented.
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© 1982 The Humana Press Inc.
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Jamison, M.H. et al. (1982). Pancreas and Copper Metabolism The Influence of Pancreatic Secretions on Cu Metabolism. In: Sorenson, J.R.J. (eds) Inflammatory Diseases and Copper. Experimental Biology and Medicine, vol 2. Humana Press. https://doi.org/10.1007/978-1-4612-5829-2_55
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DOI: https://doi.org/10.1007/978-1-4612-5829-2_55
Publisher Name: Humana Press
Print ISBN: 978-1-4612-5831-5
Online ISBN: 978-1-4612-5829-2
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