Immunologic Tests for Diagnosis and Monitoring of Defects in Cell-Mediated Immunity

  • H. Hugh Fudenberg
  • Steven D. Douglas
  • Charles L. Smith
Part of the Contemporary Immunology book series (CONTIM)


The recent explosion of knowledge about the functions of the human immune system—in its cellular and molecular aspects— has permitted more frequent diagnosis and more precise definition of clinical immunodeficiencies. The definition of particular defects by immunological and biochemical means has in addition led to the development of rational therapeutic approaches, such as replacement therapy and immunomodulation (Fudenberg and Wybran, 1980). Advances in these areas have been applied to the diagnosis and treatment of defects in cell-mediated immunity (CMI) in human patients.


Migration Inhibitory Factor Ataxia Telangiectasia Immunologic Test Suppressor Cell Activity Heterologous Antiserum 
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Copyright information

© The Humana Press Inc. 1982

Authors and Affiliations

  • H. Hugh Fudenberg
    • 1
  • Steven D. Douglas
    • 2
  • Charles L. Smith
    • 1
  1. 1.Department of Basic and Clinical Immunology and MicrobiologyMedical University of South Carolina, CharlestonUSA
  2. 2.Division of Allergy-ImmunologyThe Children’s Hospital of PhiladelphiaPhiladelphiaUSA

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