Abstract
This chapter describes the principal classes of antibiotics and attempts to demonstrate the relationships that exist between their chemical structures and their biological properties, especially their antibacterial activities, mechanisms of resistance, and toxicological profile. Knowledge of these relationships provides the basis for a rational search for new derivatives. Chemical modification of the antibiotics is a method for translating information obtained in this type of study into practical use, resulting in development of new products with more effective therapeutic properties.
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© 1982 Springer-Verlag New York, Inc.
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Lancini, G., Parenti, F. (1982). Activities of the Antibiotics in Relation to Their Structures. In: Antibiotics. Springer Series in Microbiology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-5674-8_5
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DOI: https://doi.org/10.1007/978-1-4612-5674-8_5
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-5676-2
Online ISBN: 978-1-4612-5674-8
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