Abstract
The cells of origin of teratomas arising in the gonads or extragonadal sites have been a matter of controversy from early days of scientific medicine until now. However, only recently has this discussion been supported with solid scientific evidence.
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References
Abell MR, Fayos JV, Lampe I (1965) Retroperitoneal germinomas (seminomas) without evidence of testicular involvement. Cancer 18:273–290
Atkin NB (1973) Y bodies and similar fluorescent chromocentres in human tumors including teratomata. Br J Cancer 27:183–189
Birch JM (1980) Anencephaly in stillborn sibs of children with germ cell tumors. Lancet i:1257
Brosman S, Gondos B (1974) Testicular tumors in children. Rev. Paediatri. Urol 133–171
Byskov AG, Saxen L (1976) Induction of meiosis in fetal mouse testis in vitro. Dev Biol 52:193–200
Chaussain JL, Lemerle J, Roger M, Canlorbe P, Job JC (1980) Klinefelter syndrome, tumor and sexual precocity. J Pediatr 97:607–609
Corfman PA, Richart RM (1964) Chromosome number and morphology of benign ovarian cystic teratomas. N Engl J Med 271:1241–1244
Davis CJ (1981) Personal communication
Dehner L (1973) Intrarenal teratoma occuring in infancy: report of a case with discussion of extragonadal germ cell tumors in infancy. J Pediatr. Surg 8:369–378
Eppig JJ, Kozak LP, Eicher EM, Stevens LC (1977) Ovarian teratomas in mice are derived from oocytes that have completed the first meiotic division. Nature 269:517–518
Floret D, Renaud H, Monnet P (1979) Sexual precocity and thoratic polyembryoma: Klinefelter syndrome. J Pediatr 94:163
Friedman NB (1947) Germinoma of the pineal: its identity with germinoma (seminoma) of the testis. Cancer Res 7:363–368
Friedman NB (1951) The comparative morphogenesis of extragenital and gonadal teratoid tumors. Cancer 4:265–276
Galton M, Benirschke K (1959) Forty-six chromosomes in an ovarian teratoma. Lancet ii:761–762
Gartler SM, Andina RJ (1976) Mammalian X-chromosome inactivation. Adv Hum Genet 7:99–140
Gross RE, Clatworthy HW, Meeker IA (1951) Sacrococcygeal teratomas in infants and children. Surg Gynec Obstet 92:341–354
Hunter WF, Lennox B (1954) The sex of teratoma. Lancet ii:633–634
Kaplan CG, Askin FB, Benirschke K (1979) Cytogenetics of extragonadal tumors. Teratology 19:261–266
Lennox B (1960) Nuclear sexing and the intersexes. Recent Adv. Pathol, seventh edition, Little Brown and Company, Boston
Linder D, Gartler SM (1965) Glucose-6-phosphate dehydrogenase mosaicism: utilization as a cell marker in the study of leiomyomas. Science 150:67–69
Linder D (1969) Gene loss in human teratomas. Proc Natl Acad Sci USA 63:699–704
Linder D, Power J (1970) Further evidence for post-meiotic origin of teratomas in the human female. Ann Hum Genet 34:21–30
Linder D, McCaw BK, Hecht F (1975) Parthenogenic origin of benign ovarian teratomas. New Eng J Med 292:63–66
Linder D, Hecht F, McCaw BK, Campbell JR (1975) Origin of extragonadal teratomas and endodermal sinus tumors. Nature 254:597–598
Lyon MF (1961), Gene action in the X-chromosome of the mouse. Nature 190:372–373
Martineau M (1966) A similar marker chromosome in testicular tumors. Lancet ii:839–841
Martineau M (1969) Chromosomes in human testicular tumors. J Path 99:271–282
Mintz B, Russell ES (1957) Gene-induced embryological modifications of primordial germ cells in the mouse. J Exp Zool 134:207–237
O’Gara RW, Horn RC, Enterline HT (1958) Tumors of the anterior mediastinum. Cancer 11:562–590
Pierson M, Gilgenkrantz S, Soborio M, Worms AM (1975) Syndrome de Klinefelter-Trilogie de fallot teratome du mediastin et puberte precoce. Pediatrie (Lyon) 30:185–192
Russell DS (1944) The pinealoma: its relationship to teratoma. J Path 56:145–150
Scully RE (1970) Gonadoblastoma: a review of 74 cases. Cancer 25:1340–1354
Stevens LC, Vamum DS (1974) The development of teratomas from parthenoge- netically activated ovarian mouse eggs. Develop Biol 37:369–380
Taylor AI (1963) Nuclear sex of embryonic tumors. British Med J 30:377–378
Vamum DS (1981) Personal communication
Wang N, Trend B, Bronson DL, Fraley EE (1980) Non-random abnormalities in chromosome 1 in human testicular cancers. Cancer Res 40:796–802
Wang N, Perkins KL, Bronson DL, Fraley EE (1981) Cytogenetic evidence for premeiotic transformation of human testicular cancers. Cancer Res 41::2135–2140
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© 1983 The HUMANA Press Inc.
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Linder, D. (1983). The Origin of Teratomas. In: Damjanov, I., Knowles, B.B., Solter, D. (eds) The Human Teratomas. Contemporary Biomedicine, vol 3. Humana Press. https://doi.org/10.1007/978-1-4612-5628-1_3
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DOI: https://doi.org/10.1007/978-1-4612-5628-1_3
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